Curly coat is a common trait in many dog breeds. In 2009 a mutation in exon 2 of the Keratin 71 gene (KRT71) was detected which causes the curly coat phenotype. Screening of this variant in various dog breeds revealed however, that it does not explain the curly coat in all breeds. Continued research lead to the detection of a second curly coat variant in exon 7 of the KRT71 gene. This mutation is fixed in Curly Coat Retrievers and segregates in some other breeds. Additionally, there is some indication that the variant possibly represents a genetic risk factor for some forms of follicular dysplasia in dogs.
Test specific information
Most coat colours and coat types are usually visible directly after birth.
Turn Around Time
The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.
Location of disease or trait
Genetic factors influencing coat colours and coat types are usually visible on the outside of an individual. Several factors may be hidden by the external variation.
This DNA test is available for the following breeds: Bichon Frise, Chesapeake Bay Retriever, Curly-Coated Retriever, Irish Terrier, Lagotto Romagnolo (Romagna Water Dog), Mudi, Poodle, Spanish Water Dog. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Swab, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
Coat colours and coat types are based on many genetic factors. For each factor, a separate test result will be returned.
Various genetic factors influencing coat colour and coat types are inherited in a dominant or recessive mode. Coat colours are influenced by a large number of genetic factors.
Severity of Disease
Factors influencing coat colour and coat types are usually not related to diseases.