Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests.
Test specific information
This test is performed by OPTIGEN.
The disease may show itself on different ages, in which it cannot be estimated when the first symptoms may show themselves. Differences may exist between littermates, and between breeds.
Turn Around Time
The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.
Location of disease or trait
This disease mainly affects vision, and may result in blindness.
This DNA test is available for the following breeds: American Eskimo Dog , Australian Cattle Dog, Swedish Lapphund , Portuguese Water Dog , Nova Scotia Duck Tolling Retriever, Miniature and Toy Poodle , Lapponian Herder, Labrador Retriever, Labradoodle, Kuvasz, Golden Retriever, Finnish Lapphund , Entlebucher Mountain Dog , English Cocker Spaniel, Chinese Crested, Chesapeake Bay Retriever, Australian Stumpy Tail Cattle Dog, Australian Shepherd, Spanish Water Dog , American Cocker Spaniel , Markiesje, Miniature American Sheperd, Schipperke, Yorkshire Terrier, Goldendoodle, Karelian Beardog, Australian Labradoodle, Giant Schnauzer, Cockapoo, Dwarf Poodle, Australian Shepherd Miniature & Toy, Lab/Golden Cross, Moyen Poodle, Australian Silky Terriër, Norwegian Elkhound, Portuguese Podengo Pequeno, Black Russian Terrier, Coton de Tulear, Jack Russell Terrier, Japanese Chin, Lagotto Romagnolo (Romagna Water Dog), Lancashire Heeler, Wolfspitz, Tibetian Terrier, Manchester Terrier, Hungarian Puli, Bolognese, Field Spaniel, Norrbottenspitz, Russian-European Laika, Serbian Hound, Xoloitzcuintli, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian. Additional information is available in the Frequently Asked Questions (FAQ).
For this DNA test we accept the following materials: Semen, Blood EDTA, Blood Heparin, Tissue, Swab. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.
An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.
An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.
An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.
This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).
Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.
Severity of Disease