Dr. van Haeringen Laboratorium B.V.

P306 Dwarfism ACAN D1, D2, D3 improved, D4

Background

Ponies and Miniature horses differ from full size horses only by their stature. The different breeds have been developed by selection for a propionate short stature. The reduced size is the cumulative effect of hundreds of genes, each having a small impact on stature. Some genes however, can reduce stature rapidly and have negative impact on health and reproduction. In the Miniature horse breed, mutations found within the ACAN gene are causative for Chondrodysplasia-like deformities of the cartilage, causing subsequent abnormal growth and maturation of bone.

Test specific information

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Age

Symptoms will develop at a young age. Within a few hours to a maximum of several weeks after birth, the characteristics that go with these genetic effects will become visible.

Turn Around Time

The turn-around-time of a test depends to a large extent on the logistics of sample transportation to the laboratory. After receiving the sample at the test location, you can normally expect the result within 10 working days. A longer delivery time applies to tests carried out by a Partner Lab.

Location of disease or trait

This disease is present in the entire body, but causes main effects in the internal organs such as stomach, intestinal tract, liver and / or kidneys. In a number of cases, the disease affects one major internal organ.

Breed dependence

This DNA test is available for the following breeds: Miniature Horse. Additional information is available in the Frequently Asked Questions (FAQ).

Sample type

For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Hair, Tissue. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.

Result

Inheritance

This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).

Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.

Severity of Disease

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Code P306

Dwarfism ACAN D1, D2, D3 improved, D4

€ 47,80 (Incl. 21% VAT)
€ 39,50 (Excl. VAT)
Quantity