Dr. van Haeringen Laboratorium B.V.

Search test(s) for your breed

Breed
Include tests which are not breed specific
Genome Scan Breed Price (incl. VAT) Order
i H692 CanineHD Whole-Genome Genotyping All breeds On request
- More information...
Kinship, Parentage and Identity Breed Price (incl. VAT) Order
i H691 Breed Identification Dog (partnerlab) All breeds € 135,94
Each dog is unique with its individual physical and behavioral traits resulting from various factors like genetics, training and environment. This breed identification test can provide an insight into the breed ancestry of your dog. The test identifies the genetic breed makeup of all the possible pedigree trees in the last three generations and predicts the adult weight of your dog. The potential breeds in the ancestry of your dog are determined by analyzing more than 1800 genetic markers. Testing procedures were designed to provide reliable and accurate results. This breed identification test is based upon a database of more than 350 validated breeds. If your dog contains other breeds, which are not actually available in the database, it may result in the identification of breeds, or a combination of breeds, related to the breeds in the ancestry of your dog. More information...
i H205 DNA Profile Dog All breeds € 47,64
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including animals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual. The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical. More information...
i H255 DNA Profile Dog (ASCA) Australian Shepherd, Australian Shepherd Miniature & Toy € 41,80
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including mammals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual.

The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical.
More information...
i H202 Maternity Verification Dog All breeds € 47,64
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including animals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual. The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical. More information...
i H262 Maternity verification dog (ASCA) All breeds € 41,80
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including mammals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual.

The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical.

If the DNA profile of the parent(s) is performed in a laboratory other than VHL / CTG / VHP, it can occur the profile of the offspring can't be compared with the profiles of the parents. The reason can be the testing of other hereditary characteristics at the other laboratory.
More information...
i H200 Parentage Verification Dog All breeds € 47,64
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including animals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual. The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5%. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical. More information...
i H259 Parentage verification dog (ASCA) All breeds € 41,80
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including mammals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual.

The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical.

If the DNA profile of the parent(s) is performed in a laboratory other than VHL / CTG / VHP, it can occur the profile of the offspring can't be compared with the profiles of the parents. The reason can be the testing of other hereditary characteristics at the other laboratory.
More information...
i H201 Paternity Verification Dog All breeds € 47,64
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including animals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual. The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical. More information...
i H263 Paternity verification dog (ASCA) All breeds € 41,80
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including mammals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual.

The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical.

If the DNA profile of the parent(s) is performed in a laboratory other than VHL / CTG / VHP, it can occur the profile of the offspring can't be compared with the profiles of the parents. The reason can be the testing of other hereditary characteristics at the other laboratory.
More information...
Combination Packages Breed Price (incl. VAT) Order
i H516 CombiBreed Airedale Terrier Airedale Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H521 CombiBreed Akita Akita € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H522 CombiBreed Alaskan Malamute Alaskan Malamute € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H495 Polyneuropathy 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H597 CombiBreed American Akita Akita € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H512 CombiBreed American Cocker Spaniel American Cocker Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H510 Skeletal Dysplasia 2 (SD2)
H704 prcd PRA (partnerlab)
H717 PFK (Phosphofructokinase Deficiency)
H743 Von-Willebrands Disease Type 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H601 CombiBreed American Staffordshire Terrier American Staffordshire Terrier (AmStaff) € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H312 Craniomandibular Osteopathy (CMO)
H357 Cone Rod Dystrophy 1 (crd1)
H358 Cone Rod Dystrophy 2 (crd2)
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H804 Cerebellar Ataxia / NCL-A
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H523 CombiBreed Australian Cattle Dog Australian Cattle Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H487 Brachyury (Bobtail)
H498 Myotonia Congenita 2
H511 rcd4 PRA
H644 Cystinuria, type II - A
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H623 CombiBreed Australian Labradoodle Labrador Retriever, Poodle € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H317 Macular Corneal Dystrophy
H364 Hypocatalasia
H421 Hiplaxity 2
H427 MTM
H441 Thrombocytopaenia
H490 Gangliosidosis, GM2, type II
H510 Skeletal Dysplasia 2 (SD2)
H511 rcd4 PRA
H643 Cystinuria, type II - A - 1
H672 Exercise Induced Collapse, EIC (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H675 HNPK (partner lab)
H677 Von-Willebrands Disease Type 1
H698 Narcolepsy 3
H704 prcd PRA (partnerlab)
H741 Pyruvate kinase Deficiency (PKDef)
H743 Von-Willebrands Disease Type 2
H746 Maligne Hyperthermia
H749 Centronuclear Myopathy (CNM, also known as HMLR)
H794 Retinal Dysplasia Retinal Folds RD OSD 1
H811 Hyperuricemia (HUU)
H812 Neonatal Encephalopathy
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H321 CombiBreed Australian Shepherd Australian Shepherd € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H330 Neuronal ceroid lipofuscinosis (NCL) 6
H332 IGS (Selective Cobalamin Malabsorption) 3
H421 Hiplaxity 2
H487 Brachyury (Bobtail)
H629 MDR1 (partner lab)
H672 Exercise Induced Collapse, EIC (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H746 Maligne Hyperthermia
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H524 CombiBreed Basenji Basenji € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H371 PRA
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H525 CombiBreed Basset Hound Basset € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H353 Coat Colour Saddle tan vs black-and-tan
H421 Hiplaxity 2
H435 Factor VII deficiency
H442 Thrombopathia
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H526 CombiBreed Beagle Beagle € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H364 Hypocatalasia
H366 IGS (Selective Cobalamin Malabsorption) 1
H413 Cerebellar Abiotrophy (NCCD)
H421 Hiplaxity 2
H424 Musladin-Lueke syndrome (MLS)
H430 Osteogenesis imperfecta
H435 Factor VII deficiency
H455 Pyruvatekinase Deficiency (PKDef) 3
H496 Glaucoma (POAG)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H620 CombiBreed Bearded Collie Bearded Collie € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H367 IGS (Selective Cobalamin Malabsorption) 2
H421 Hiplaxity 2
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H721 Neuronal ceroid lipofuscinosis (NCL) 5
H787 Trapped Neutrophil Syndrome (TNS)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H513 CombiBreed Belgium Shepherd Dog Belgian Shepherd € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H331 Cerebellar Ataxia (SDCA1)
H354 Coat Colour Panda White Spotting
H421 Hiplaxity 2
H484 CLAD, Type III
H489 Dermatofibrosis
H491 Haemophilia A (Factor VIII) (partner lab)
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H746 Maligne Hyperthermia
H748 Mucopolysaccharidosis Type VII
H811 Hyperuricemia (HUU)
H847 Coat Colour D-Locus Improved (MLPH)
H872 Pituitary dwarfism
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H528 CombiBreed Bernese Mountain Dog Bernese Mountain Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H308 Degenerative Myelopathy 2 (DM2 Bernese mountain)
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H529 CombiBreed Bichon Frise Bichon Frise € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H450 Bleeding disorder due to P2RY12 defect
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H538 CombiBreed Bloodhound Bloodhound € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H319 CombiBreed Border Collie Border Collie € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H327 Dental Hypomineralization (Raine Syndrome)
H367 IGS (Selective Cobalamin Malabsorption) 2
H388 Sensory Neuropathy
H421 Hiplaxity 2
H472 Goniodysgenesis and glaucoma
H629 MDR1 (partner lab)
H644 Cystinuria, type II - A
H673 Degenerative Myelopathy, DM (partner lab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H721 Neuronal ceroid lipofuscinosis (NCL) 5
H746 Maligne Hyperthermia
H787 Trapped Neutrophil Syndrome (TNS)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

More information...
i H602 CombiBreed Border Terrier Border Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H603 CombiBreed Boston Terrier Boston Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H699 Hereditary Cataract 2 (HSF4)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H532 CombiBreed Bouvier des Ardennes Bouvier des Ardennes € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H592 CombiBreed Bouvier des Flandres Bouvier des Flandres € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H545 CombiBreed Boxer Boxer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H550 CombiBreed Brittany Spaniel Brittany Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H412 C3 Deficiency
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H605 CombiBreed Bull Terrier Miniature Bull Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H463 Lethal Acrodermatitis (LAD)
H509 Polycystic kidney disease (PKD1)
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H534 CombiBreed Bullmastiff Bull Mastif € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H739 Dominant PRA
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H604 CombiBreed Cairn Terrier Cairn Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H312 Craniomandibular Osteopathy (CMO)
H360 Gallbladder Mucocele
H421 Hiplaxity 2
H677 Von-Willebrands Disease Type 1
H737 Globoid Cell Leukodystrophy / Krabbes Disease
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H536 CombiBreed Cavalier King Charles Spaniel Cavalier King Charles Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H359 Muscular Dystrophy, Duchenne Type (DMD)
H421 Hiplaxity 2
H441 Thrombocytopaenia
H673 Degenerative Myelopathy, DM (partner lab)
H674 Episodic Falling Disease (partner lab)
H717 PFK (Phosphofructokinase Deficiency)
H811 Hyperuricemia (HUU)
H913 Dry Eye Curly Coat Syndrome
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H519 CombiBreed Chihuahua Chihuahua € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H630 Coat Colour Merle (partner lab)
H743 Von-Willebrands Disease Type 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H514 CombiBreed Chinese Crested Dog Chinese Crested € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H770 rcd3 PRA
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H685 Combibreed Collie Smooth Smooth Collie € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H367 IGS (Selective Cobalamin Malabsorption) 2
H421 Hiplaxity 2
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H721 Neuronal ceroid lipofuscinosis (NCL) 5
H787 Trapped Neutrophil Syndrome (TNS)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H621 CombiBreed Collie, Rough Rough Collies € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H367 IGS (Selective Cobalamin Malabsorption) 2
H421 Hiplaxity 2
H629 MDR1 (partner lab)
H630 Coat Colour Merle (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H721 Neuronal ceroid lipofuscinosis (NCL) 5
H752 Gray Collie Syndrome (Cyclic Neutropenia)
H787 Trapped Neutrophil Syndrome (TNS)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H551 CombiBreed Continental Toy Spaniel - Papillon Continental Toy Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H348 PAP-PRA1
H421 Hiplaxity 2
H677 Von-Willebrands Disease Type 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H593 CombiBreed Continental Toy Spaniel - Phalène Phalene € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H348 PAP-PRA1
H421 Hiplaxity 2
H677 Von-Willebrands Disease Type 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H539 CombiBreed Coton de Tulear Coton de Tulear € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H374 Primary Hyperoxaluria
H410 Cerebellar Ataxia
H421 Hiplaxity 2
H672 Exercise Induced Collapse, EIC (partner lab)
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H730 CMR2 (Canine Multifocal Retinopathy)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H515 CombiBreed Dachshund Short-Haired Dachshund, Miniature Smoothhaired Dachshund, Miniature Longhaired Dachshund, Longhair Dachshunds, Dachshund € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H372 PRA crdPRA
H418 Mucopolysaccharidosis Type IIIa
H421 Hiplaxity 2
H431 Osteogenesis imperfecta 2
H435 Factor VII deficiency
H494 Neuronal ceroid lipofuscinosis (NCL) 1
H499 Neuronal ceroid lipofuscinosis (NCL) 2
H630 Coat Colour Merle (partner lab)
H707 Narcolepsy 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H540 CombiBreed Dalmatian Dalmatier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H546 CombiBreed Dobermann Dobermann, Doberman Pinscher € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H434 Dilated Cardiomyopathy (DCM)
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H697 Narcolepsy 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H547 CombiBreed Dogo Argentino Dogo Argentino € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H548 CombiBreed Dogue de Bordeaux Dogue de Bordeaux € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H444 Palmoplantar keratoderma 1 (FNEPPK1)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H582 CombiBreed Dutch Schapendoes Schapendoes € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H915 gPRA
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H518 CombiBreed Dutch Shepherd Dog Dutch Shepherd Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H354 Coat Colour Panda White Spotting
H421 Hiplaxity 2
H484 CLAD, Type III
H489 Dermatofibrosis
H491 Haemophilia A (Factor VIII) (partner lab)
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H746 Maligne Hyperthermia
H748 Mucopolysaccharidosis Type VII
H811 Hyperuricemia (HUU)
H847 Coat Colour D-Locus Improved (MLPH)
H872 Pituitary dwarfism
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H533 CombiBreed English Bulldog American Bulldog, English Bulldog, French Bulldog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H378 Ichthyosis 4
H421 Hiplaxity 2
H429 Neuronal ceroid lipofuscinosis (NCL) 10
H673 Degenerative Myelopathy, DM (partner lab)
H699 Hereditary Cataract 2 (HSF4)
H746 Maligne Hyperthermia
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H598 CombiBreed English Cocker Spaniel English Cocker Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H336 Sensory Neuropathy 3 AMS
H360 Gallbladder Mucocele
H421 Hiplaxity 2
H676 FN, Familial Nephropathy (partner lab)
H704 prcd PRA (partnerlab)
H717 PFK (Phosphofructokinase Deficiency)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H549 CombiBreed English Pointer Pointer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H336 Sensory Neuropathy 3 AMS
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H599 CombiBreed English Springer Spaniel English Springer Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H336 Sensory Neuropathy 3 AMS
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H432 Tremor, X-linked
H704 prcd PRA (partnerlab)
H717 PFK (Phosphofructokinase Deficiency)
H736 Fucosidosis
H766 crd4-PRA (previously cord1-PRA)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H474 CombiBreed FCI Group 01 Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Bearded Collie, Bobtail, Border Collie, Bouvier des Flandres, Briard, Cardigen Welsh Corgi, Collies, German Shepherd, Mudi, Kuvasz, Lancashire Heeler, Lapponian Herder, Miniature American Sheperd, Old English Sheepdog, Pembroke Welsh Corgi, Polish Lowland Sheepdog (Polski Owczarek Nizinny - PON), Saarloos Wolfhond, Schapendoes, Schipperke, Sheltie, Czechoslovakian Wolfdog, Wäller, Welsh Corgi, White Swiss Shepherd Dog (Berger Blank Suisse), Belgian Shepherd, Smooth Collies, Rough Collies, Pyrenean Shepherd € 69,88
The Combination Pack CombiBreed Group 01 is assembled for dogs within the FCI Breedgroup 1, Sheepdogs and Cattle Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H306 Multifocal Retinopathy 3 (cmr3) 1
H307 Multifocal Retinopathy 3 (cmr3) 2
H324 FBN2
H360 Gallbladder Mucocele
H367 IGS (Selective Cobalamin Malabsorption) 2
H414 Primary Ciliary dyskinesia
H421 Hiplaxity 2
H434 Dilated Cardiomyopathy (DCM)
H484 CLAD, Type III
H487 Brachyury (Bobtail)
H489 Dermatofibrosis
H498 Myotonia Congenita 2
H677 Von-Willebrands Disease Type 1
H721 Neuronal ceroid lipofuscinosis (NCL) 5
H728 CSNB (Congenital Stationary Night Blindness)
H743 Von-Willebrands Disease Type 2
H745 X-SCID
H748 Mucopolysaccharidosis Type VII
H752 Gray Collie Syndrome (Cyclic Neutropenia)
H770 rcd3 PRA
H787 Trapped Neutrophil Syndrome (TNS)
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H871 CMR1 (Canine Multifocal Retinopathy)
H872 Pituitary dwarfism
H915 gPRA
H919 Hiplaxity 1
More information...
i H475 CombiBreed FCI Group 02 Bernese Mountain Dog, Boxer, Bull Mastif, Cane Corso, Great Dane, Danish-Swedish Farmdog, Doberman Pinscher, German Pinscher, English Bulldog, Entlebucher Mountain Dogs, Landseer, Mastiffs, Miniature Pinscher, Miniature Schnauzer, New Foundlander, Austrian Pinscher, Perro de Presa Canarios, Schnauzer, Black Russian Terrier, Boerboel, Kraski Ovcar, Giant Schnauzer, Great Pyrenees, Dobermann € 69,88
The Combination Pack CombiBreed Group 02 is assembled for dogs within the FCI Breedgroup 2, Pinscher and Schnauzer - Molossoid Breeds - Swiss Mountain and Cattle Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H304 Ichthyosis 3
H308 Degenerative Myelopathy 2 (DM2 Bernese mountain)
H324 FBN2
H329 Juvenile Laryngeal Paralysis Polyneuropathy (JLPP)
H421 Hiplaxity 2
H428 Neuroaxonal Dystrophy
H434 Dilated Cardiomyopathy (DCM)
H447 Thrombasthenia 2
H449 Thrombopathia 3
H450 Bleeding disorder due to P2RY12 defect
H487 Brachyury (Bobtail)
H697 Narcolepsy 2
H703 Cystinuria I - A - 1
H738 Myotonia Congenita
H739 Dominant PRA
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1
More information...
i H476 CombiBreed FCI Group 03 American Staffordshire Terrier (AmStaff), Bedlington Terrier, Cairn Terrier, Fox Terrier, Glen of Imaal Terrier, Jack Russell Terrier, Kerru Blue Terrier, Manchester Terrier, Scottish Terrier, Staffordshire Bull Terrier, Terrier, Westhighland White Terrier € 69,88
The Combination Pack CombiBreed Group 03 is assembled for dogs within the FCI Breedgroup 3, Terriers. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H303 Spinocerebellar ataxia
H312 Craniomandibular Osteopathy (CMO)
H324 FBN2
H357 Cone Rod Dystrophy 1 (crd1)
H358 Cone Rod Dystrophy 2 (crd2)
H360 Gallbladder Mucocele
H363 Hyperkeratosis, epidermolytic
H421 Hiplaxity 2
H423 SCID
H485 Congenital Hypothyroidism (CHG) 2
H488 Congenital Hypothyroidism (CHG) 3
H492 Hyperkeratosis, palmoplantar
H509 Polycystic kidney disease (PKD1)
H677 Von-Willebrands Disease Type 1
H699 Hereditary Cataract 2 (HSF4)
H724 L2-HGA
H744 Von-Willebrands Disease Type 3
H804 Cerebellar Ataxia / NCL-A
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1
More information...
i H477 CombiBreed FCI Group 04 Miniature Smoothhaired Dachshund, Short-Haired Dachshund, Miniature Longhaired Dachshund, Wire Haired Dachshund, Dachshund € 69,88
The Combination Pack CombiBreed Group 04 is assembled for dogs within the FCI Breedgroup 4, Dachshunds. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H372 PRA crdPRA
H418 Mucopolysaccharidosis Type IIIa
H421 Hiplaxity 2
H431 Osteogenesis imperfecta 2
H435 Factor VII deficiency
H494 Neuronal ceroid lipofuscinosis (NCL) 1
H499 Neuronal ceroid lipofuscinosis (NCL) 2
H766 crd4-PRA (previously cord1-PRA)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1
More information...
i H478 CombiBreed FCI Group 05 Alaskan Malamute, Basenji, Chow Chow, Finnish Lapphund, Karelian Beardog, Wolfspitz, Norwegian Elkhound, Samoyed, Shiba Inu, Volpino Italiano, Swedish Lapphund, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 69,88
The Combination Pack CombiBreed Group 05 is assembled for dogs within the FCI Breedgroup 5, Spitz and Primitive types. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H356 Chondrodysplasia, Disproportionate Short-Limbed
H360 Gallbladder Mucocele
H382 PRA erd
H383 Primary Glaucoma
H421 Hiplaxity 2
H433 Vitamin D-deficiency rickets, type II
H487 Brachyury (Bobtail)
H495 Polyneuropathy 2
H496 Glaucoma (POAG)
H677 Von-Willebrands Disease Type 1
H702 GM1
H743 Von-Willebrands Disease Type 2
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1
More information...
i H479 CombiBreed FCI Group 06 Beagle, Basset, Dalmatier, Rhodesian Ridgeback € 69,88
The Combination Pack CombiBreed Group 06 is assembled for dogs within the FCI Breedgroup 6, Scenthounds and Related Breeds. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H364 Hypocatalasia
H366 IGS (Selective Cobalamin Malabsorption) 1
H411 Cerebellar Ataxia, progressive early-onset
H421 Hiplaxity 2
H424 Musladin-Lueke syndrome (MLS)
H435 Factor VII deficiency
H442 Thrombopathia
H455 Pyruvatekinase Deficiency (PKDef) 3
H496 Glaucoma (POAG)
H607 Factor IX Deficiency
H745 X-SCID
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1
More information...
i H480 CombiBreed FCI Group 07 Braque du Bourbonnais, Drentsche Patrijshond, German Wirehaired Pointer, German Shorthaired Pointer, German Longhaired Pointer, English Setter, Gordon Setter, Large Munsterlander, Irish Red and White Setter, Irish setter, Small Munsterlander, Old Danish Pointer, Stabijhoun, Weimaraner, Magyar Vizsla € 69,88
The Combination Pack CombiBreed Group 07 is assembled for dogs within the FCI Breedgroup 7, Pointing Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H318 Cerebellar Cortical Degeneration
H324 FBN2
H412 C3 Deficiency
H421 Hiplaxity 2
H425 Congenital Myasthenic Syndrome
H487 Brachyury (Bobtail)
H511 rcd4 PRA
H652 Neuronal ceroid lipofuscinosis (NCL) 8-1
H677 Von-Willebrands Disease Type 1
H709 CLAD, Type I
H743 Von-Willebrands Disease Type 2
H768 rcd1 PRA
H811 Hyperuricemia (HUU)
H918 Cone Degeneration
H919 Hiplaxity 1
More information...
i H481 CombiBreed FCI Group 08 American Cocker Spaniel, Chesapeake Bay Retriever, Clumber Spaniel, Cocker Spaniel, Curly-Coated Retriever, English Springer Spaniel, Flat-Coated Retriever, Golden Retriever, Labrador Retriever, Lagotto Romagnolo (Romagna Water Dog), Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, Spanish Water Dog, Sussex Spaniel, Frisian Water Dogs € 69,88
The Combination Pack CombiBreed Group 08 is assembled for dogs within the FCI Breedgroup 8, Retrievers - Flushing Dogs - Water Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H360 Gallbladder Mucocele
H375 Dog_Skin Fragility
H416 Congenital Hypothyroidism (CHG) 1
H421 Hiplaxity 2
H427 MTM
H432 Tremor, X-linked
H456 SCID 2
H473 GR_PRA2
H486 Epilepsy, BFJ
H510 Skeletal Dysplasia 2 (SD2)
H511 rcd4 PRA
H698 Narcolepsy 3
H717 PFK (Phosphofructokinase Deficiency)
H736 Fucosidosis
H740 Pyruvate Dehydrogenase Phosphatase 1 (PDP1)
H741 Pyruvate kinase Deficiency (PKDef)
H749 Centronuclear Myopathy (CNM, also known as HMLR)
H811 Hyperuricemia (HUU)
H868 GR_PRA1
H873 Ichthyosis 2
H919 Hiplaxity 1
More information...
i H482 CombiBreed FCI Group 09 Cavalier King Charles Spaniel, Chihuahua, Chinese Crested, Coton de Tulear, French Bulldog, Havanese, Lhaso Apso, Maltese, Markiesje, Miniature and Toy Poodle, Pug Dog, Papillion, Phalene, Poodle, Shih Tzu, Tibet Spaniel, Tibetian Terrier € 69,88
The Combination Pack CombiBreed Group 09 is assembled for dogs within the FCI Breedgroup 9, Companion and Toy Dogs. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H348 PAP-PRA1
H364 Hypocatalasia
H410 Cerebellar Ataxia
H415 Glycogen Storage Disease GSD I
H421 Hiplaxity 2
H439 Prekallikrein deficiency
H441 Thrombocytopaenia
H454 Pyruvatekinase Deficiency (PKDef) 2
H490 Gangliosidosis, GM2, type II
H496 Glaucoma (POAG)
H730 CMR2 (Canine Multifocal Retinopathy)
H743 Von-Willebrands Disease Type 2
H811 Hyperuricemia (HUU)
H812 Neonatal Encephalopathy
H849 Primary Lens Luxation (PLL)
H913 Dry Eye Curly Coat Syndrome
H919 Hiplaxity 1
More information...
i H483 CombiBreed FCI Group 10 Afghan Hound, Galgo Espanol, Greyhound, Irish Wolfhound, Longhaired Whippets, Saluki, Sloughi, Whippet € 69,88
The Combination Pack CombiBreed Group 10 is assembled for dogs within the FCI Breedgroup 10, Sighthounds. This package covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website.

This Combination Package contains the following markers:
H324 FBN2
H421 Hiplaxity 2
H493 Muscular hypertrophy (double muscling)
H769 rcd1a PRA
H811 Hyperuricemia (HUU)
H914 Polyneuropathy 1
H919 Hiplaxity 1
More information...
i H591 CombiBreed Finnish Lapphund Finnish Lapphund, Suomenlapinkoira € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H306 Multifocal Retinopathy 3 (cmr3) 1
H307 Multifocal Retinopathy 3 (cmr3) 2
H347 GSDII (Pompe Disease)
H421 Hiplaxity 2
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H552 CombiBreed Flat Coated Retriever Flat-Coated Retriever € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H531 CombiBreed French Bulldog French Bulldog, English Bulldog, American Bulldog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H378 Ichthyosis 4
H421 Hiplaxity 2
H429 Neuronal ceroid lipofuscinosis (NCL) 10
H673 Degenerative Myelopathy, DM (partner lab)
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1
H699 Hereditary Cataract 2 (HSF4)

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H543 CombiBreed German Longhaired Pointer German Longhaired Pointer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H320 CombiBreed German Shepherd German Shepherd € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H354 Coat Colour Panda White Spotting
H421 Hiplaxity 2
H484 CLAD, Type III
H489 Dermatofibrosis
H491 Haemophilia A (Factor VIII) (partner lab)
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H746 Maligne Hyperthermia
H748 Mucopolysaccharidosis Type VII
H765 Hair length
H847 Coat Colour D-Locus Improved (MLPH)
H872 Pituitary dwarfism
H919 Hiplaxity 1

CombiBreed, introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H542 CombiBreed German Shorthaired Pointer German Shorthaired Pointer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H336 Sensory Neuropathy 3 AMS
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H918 Cone Degeneration
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H622 CombiBreed German Spitz Wolfspitz, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H360 Gallbladder Mucocele
H421 Hiplaxity 2
H433 Vitamin D-deficiency rickets, type II
H629 MDR1 (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H743 Von-Willebrands Disease Type 2
H746 Maligne Hyperthermia
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H541 CombiBreed German Wirehaired Pointer German Wirehaired Pointer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H322 CombiBreed Golden Retriever Golden Retriever € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H380 Neuronal ceroid lipofuscinosis (NCL) 5 GR
H381 Osteogenesis Imperfecta 3
H421 Hiplaxity 2
H473 GR_PRA2
H497 Epidermolysis bullosa, dystrophic (RDEB)
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H747 Muscular Dystrophy (GRMD)
H868 GR_PRA1
H873 Ichthyosis 2
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H553 CombiBreed Gordon Setter Gordon Setter € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H511 rcd4 PRA
H652 Neuronal ceroid lipofuscinosis (NCL) 8-1
H653 Cerebellar Ataxia 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H544 CombiBreed Great Dane Great Dane € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H304 Ichthyosis 3
H316 Coat Colour H-locus (Harlequin)
H368 Myopathy
H421 Hiplaxity 2
H677 Von-Willebrands Disease Type 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H556 CombiBreed Great Swiss Mountain Dog Great Swiss Mountain Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H450 Bleeding disorder due to P2RY12 defect
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H527 CombiBreed Griffon Belge Belgisch Griffontje € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H555 CombiBreed Griffon Bruxellois Griffon Bruxellois € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H348 PAP-PRA1
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H530 CombiBreed Havanese Havanese € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H557 CombiBreed Hovawart Hovawart € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H578 CombiBreed Hungarian Shorthaired Pointer Hungarian Shorthaired Pointer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H558 CombiBreed Irish Red Setter Irish setter € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H491 Haemophilia A (Factor VIII) (partner lab)
H511 rcd4 PRA
H652 Neuronal ceroid lipofuscinosis (NCL) 8-1
H677 Von-Willebrands Disease Type 1
H709 CLAD, Type I
H768 rcd1 PRA
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H606 CombiBreed Irish Soft Coated Wheaten Terrier Soft-Coated Wheaten Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H608 CombiBreed Irish Terrier Irish Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H492 Hyperkeratosis, palmoplantar
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H559 CombiBreed Irish Wolfhound Irish Wolfhound € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H535 CombiBreed Italian Corso Dog Cane Corso € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H573 CombiBreed Italian Greyhound Italian Greyhound € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H609 CombiBreed Jack Russell Terrier Jack Russell Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H303 Spinocerebellar ataxia
H328 Spinocerebellar ataxia, LOA (Late Onset Ataxia)
H421 Hiplaxity 2
H423 SCID
H487 Brachyury (Bobtail)
H704 prcd PRA (partnerlab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H561 CombiBreed Kooikerhondje Dutch Kooikerhondje € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H642 Von Willebrand disease 3 - 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H323 CombiBreed Labrador Retriever Labrador Retriever € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H317 Macular Corneal Dystrophy
H339 Congenital Myasthenic Syndrome
H387 Achromatopsia 3 (cone degeneration, hemeralopia)
H389 Alexander Disease
H421 Hiplaxity 2
H427 MTM
H441 Thrombocytopaenia
H473 GR_PRA2
H510 Skeletal Dysplasia 2 (SD2)
H625 Congenital Cornification Disorder
H643 Cystinuria, type II - A - 1
H672 Exercise Induced Collapse, EIC (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H675 HNPK (partner lab)
H698 Narcolepsy 3
H704 prcd PRA (partnerlab)
H741 Pyruvate kinase Deficiency (PKDef)
H746 Maligne Hyperthermia
H749 Centronuclear Myopathy (CNM, also known as HMLR)
H794 Retinal Dysplasia Retinal Folds RD OSD 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

Dr. van Haeringen Laboratorium B.V. (VHL), introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H563 CombiBreed Landseer (E.K.T.) Landseer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H449 Thrombopathia 3
H703 Cystinuria I - A - 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H564 CombiBreed Leonberger Leonberger € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H379 Polyneuropathy 3 (LPN1)
H342 Polyneuropathy 4 (LPN2)
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H565 CombiBreed Lhasa Apso Lhaso Apso € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H566 CombiBreed Maltese Maltese € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H415 Glycogen Storage Disease GSD I
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H567 CombiBreed Mastiff Mastiffs € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H730 CMR2 (Canine Multifocal Retinopathy)
H739 Dominant PRA
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H610 CombiBreed Miniature Bull Terrier Miniature Bull Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H463 Lethal Acrodermatitis (LAD)
H509 Polycystic kidney disease (PKD1)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H596 CombiBreed Miniature Pinscher Miniature Pinscher € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H645 Cystinuria, type II - B
H809 Hereditary Cataract (HC) - HSF4
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H568 CombiBreed Neapolitan Mastiff Neapolitan Mastiff € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H569 CombiBreed Newfoundland New Foundlander € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H703 Cystinuria I - A - 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H611 CombiBreed Norfolk Terrier Norfolk Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H363 Hyperkeratosis, epidermolytic
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H570 CombiBreed Nova Scotia Duck Tolling Retriever Nova Scotia Duck Tolling Retriever € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H571 CombiBreed Old English Sheepdog (Bobtail) Old English Sheepdog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H414 Primary Ciliary dyskinesia
H421 Hiplaxity 2
H629 MDR1 (partner lab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H612 CombiBreed Parson Russell Terrier Parson Russel Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H303 Spinocerebellar ataxia
H328 Spinocerebellar ataxia, LOA (Late Onset Ataxia)
H421 Hiplaxity 2
H672 Exercise Induced Collapse, EIC (partner lab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H572 CombiBreed Petit Brabançon Petit Brabançon € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H554 CombiBreed Poodle Poodle € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H364 Hypocatalasia
H421 Hiplaxity 2
H490 Gangliosidosis, GM2, type II
H511 rcd4 PRA
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H743 Von-Willebrands Disease Type 2
H811 Hyperuricemia (HUU)
H812 Neonatal Encephalopathy
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H574 CombiBreed Pug Pug Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H454 Pyruvatekinase Deficiency (PKDef) 2
H677 Von-Willebrands Disease Type 1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H537 CombiBreed Pyrenean Mountain Dog Pyrenean Shepherd € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H447 Thrombasthenia 2
H487 Brachyury (Bobtail)
H811 Hyperuricemia (HUU)
H871 CMR1 (Canine Multifocal Retinopathy)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H575 CombiBreed Rhodesian Ridgeback Rhodesian Ridgeback € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H335 Juveniele Myoclonic Epilepsy
H421 Hiplaxity 2
H607 Factor IX Deficiency
H672 Exercise Induced Collapse, EIC (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H811 Hyperuricemia (HUU)
H873 Ichthyosis 2
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H562 CombiBreed Romagna Water Dog Lagotto Romagnolo (Romagna Water Dog) € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H486 Epilepsy, BFJ
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H577 CombiBreed Rottweiler Rottweiler € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H329 Juvenile Laryngeal Paralysis Polyneuropathy (JLPP)
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H579 CombiBreed Saarloos Wolfdog Saarloos Wolfhond € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H872 Pituitary dwarfism
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H590 CombiBreed Saint Bernard Saint Bernard € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H379 Polyneuropathy 3 (LPN1)
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H580 CombiBreed Saluki Saluki € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H581 CombiBreed Samoyed Samoyed € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H370 Nephritis
H421 Hiplaxity 2
H772 X Linked PRA1 (XL PRA1)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H583 CombiBreed Schipperke Schipperke € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H576 CombiBreed Schnauzer Schnauzer € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H428 Neuroaxonal Dystrophy
H459 Dilated Cardiomyopathy (DCM3)
H491 Haemophilia A (Factor VIII) (partner lab)
H682 PRA 5
H704 prcd PRA (partnerlab)
H738 Myotonia Congenita
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H585 CombiBreed Shar Pei Shar Pei € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H586 CombiBreed Shetland Sheepdog Sheltie € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H390 PRA 2
H414 Primary Ciliary dyskinesia
H421 Hiplaxity 2
H629 MDR1 (partner lab)
H630 Coat Colour Merle (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)
H744 Von-Willebrands Disease Type 3
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H587 CombiBreed Shiba Shiba Inu € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H702 GM1
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H588 CombiBreed Shih Tzu Shih Tzu € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H421 Hiplaxity 2
H439 Prekallikrein deficiency
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H589 CombiBreed Siberian Husky € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H696 Warburg Micro Syndrome 1 (WARBM1)
H772 X Linked PRA1 (XL PRA1)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H560 CombiBreed Small Munsterlander Small Munsterlander € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H613 CombiBreed Smooth Fox Terrier Smooth haired fox terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H517 CombiBreed Spanish Water Dog Spanish Water Dog € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H416 Congenital Hypothyroidism (CHG) 1
H421 Hiplaxity 2
H462 Neuroaxonal Dystrophy (Spanish Water Dog)
H487 Brachyury (Bobtail)
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H614 CombiBreed Staffordshire Bull Terrier Staffordshire Bull Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H699 Hereditary Cataract 2 (HSF4)
H724 L2-HGA
H811 Hyperuricemia (HUU)
H847 Coat Colour D-Locus Improved (MLPH)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H600 CombiBreed Tibetan Spaniel Tibet Spaniel € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H373 PRA type 3
H374 Primary Hyperoxaluria
H421 Hiplaxity 2
H717 PFK (Phosphofructokinase Deficiency)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H615 CombiBreed Tibetan Terrier Tibetian Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H373 PRA type 3
H414 Primary Ciliary dyskinesia
H421 Hiplaxity 2
H458 Neuronal ceroid lipofuscinosis (NCL) 12
H511 rcd4 PRA
H673 Degenerative Myelopathy, DM (partner lab)
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H520 CombiBreed Weimaraner Weimaraner € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H365 Hypomyelination
H377 Dog_Spinal Dysraphism
H421 Hiplaxity 2
H673 Degenerative Myelopathy, DM (partner lab)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H584 CombiBreed Welsh Corgi Pembroke Welsh Corgi € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H346 Chondrodystrophy and Intervertebral Disc Disease
H353 Coat Colour Saddle tan vs black-and-tan
H419 Muscular Dystrophy, Duchenne type (MDM)
H421 Hiplaxity 2
H487 Brachyury (Bobtail)
H672 Exercise Induced Collapse, EIC (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H677 Von-Willebrands Disease Type 1
H704 prcd PRA (partnerlab)
H745 X-SCID
H746 Maligne Hyperthermia
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H616 CombiBreed Welsh Terrier Welsh Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H492 Hyperkeratosis, palmoplantar
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H617 CombiBreed West Highland White Terrier Westhighland White Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H737 Globoid Cell Leukodystrophy / Krabbes Disease
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H595 CombiBreed Whippet Whippet € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H435 Factor VII deficiency
H493 Muscular hypertrophy (double muscling)
H717 PFK (Phosphofructokinase Deficiency)
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H618 CombiBreed Wire Fox Terrier Wire-haired Fox Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H811 Hyperuricemia (HUU)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H619 CombiBreed Yorkshire Terrier Yorkshire Terrier € 165,17
This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H421 Hiplaxity 2
H704 prcd PRA (partnerlab)
H811 Hyperuricemia (HUU)
H849 Primary Lens Luxation (PLL)
H919 Hiplaxity 1

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
i H469 Combination Pack Coat Colour All breeds € 69,88
The Combination Pack Colour covers several important traits and can be based on samples from animals at any age. Information on individual tests is available at our website. This Combination Package contains the following markers:

H733 Coat Colour B-locus
H734 Coat Colour E-locus
H818 Coat Colour Em-locus
H819 Coat Colour K-locus
H820 Coat Colour A-locus
H847 Coat Colour D-Locus Improved (MLPH)

A small possibility exists that one or two tests which are part of a combination package will not provide results. Because of the low pricing of the combination packages, we cannot retest a single marker if this marker fails in a combination package.

If a particular test is highly important to you, we recommend that you order such a marker as a single test in our webshop. If needed, repeated testing is routinely performed on all single tests without extra costs.
More information...
i H398 Combination Pack Partnerlab All breeds € 123,24
The Combination Pack Partnerlab covers several important traits and can be based on samples from This Combination Pack covers several important traits and can be based on samples from animals at any age. Information on individual tests is available through the links at the DNA tests.

One or more DNA tests of this Combination Package are performed by our partner laboratory. We would like to point out that the tests performed by our partner laboratory also can be performed via the licensee of the patent. If you want to run the tests through the licensee, you can order these tests separately.

The Combination Package contains the following markers:
H491 Haemophilia A (Factor VIII) (partner lab)
H629 MDR1 (partner lab)
H630 Coat Colour Merle (partner lab)
H673 Degenerative Myelopathy, DM (partner lab)
H672 Exercise Induced Collapse, EIC (partner lab)
H675 HNPK (partner lab)
H704 prcd PRA (partnerlab)
H705 Collie Eye Anomaly (CEA_CH, partnerlab)

CombiBreed introduces a different strategy for DNA tests for several genetic markers. Recently, technical improvements have allowed for the combination of several genetic markers in one test.
More information...
Genetic diseases Breed Price (incl. VAT) Order
i H627 Aberrant Autophagy (LSD) Lagotto Romagnolo (Romagna Water Dog) € 50,18
Autophagy is an evolutionary conserved intracellular process, which is necessary for a balance between the production of new and the degradation of old cell components. Proteins and organelles are sequestered within double-membrane autophagosomes and delivered to the lysosome for degradation. Several different autophagy related (ATG) proteins are involved in this pathway and dysfunction has been implicated in various deleterious neurodegenerative disorders. In the Lagotto Romagnolo breed, a progressive cerebellar ataxia could be traced back to a mutation in the ATG4D gene. More information...
i H386 Achromatopsia 2 (cone degeneration, hemeralopia) German Shepherd € 50,18
Achromatopsia or Cone Degeneration Disease (CD) is a rare disease causing day blindness due to degeneration of the retinal cones. CD in affected dogs can be diagnosed in the early weeks of the life. The pups become day-blind and are photophobic – meaning that exposure to bright light is irritating or even painful. The pup will shun brightly-lit areas. In contrast to PRA (Progressive Retinal Atrophy), which is the more common type of retinal disease in many dog breeds, CD does not affect night vision. More information...
i H387 Achromatopsia 3 (cone degeneration, hemeralopia) Labrador Retriever € 50,18
Achromatopsia or Cone Degeneration Disease (CD) is a rare disease causing day blindness due to degeneration of the retinal cones. CD in affected dogs can be diagnosed in the early weeks of the life. The pups become day-blind and are photophobic – meaning that exposure to bright light is irritating or even painful. The pup will shun brightly-lit areas. In contrast to PRA (Progressive Retinal Atrophy), which is the more common type of retinal disease in many dog breeds, CD does not affect night vision. More information...
i H338 Acute Respiratory Distress Syndrome (ARDS) Dalmatier € 50,18
In Dalmatian dogs, a fatal familial juvenile respiratory disease, resembling the acute respiratory distress syndrome (ARDS) was reported. The causative mutation could be identified in the ANLN gene and leads to a severe truncation of the ANLN protein. This protein is predominantly expressed in the lungs and plays an important role in the epithelial cell organization. Absence of functional ANLN protein in the lung epithelium results in disturbed cell division, which causes progressive Tachypnea and respiratory distress. More information...
i H396 Adult Onset Neuropathy (AON) (service lab) Cocker Spaniel € 79,41
<h2>Background</h2> <p style="margin:0cm 0cm 0.0001pt">Adult Onset Neuropathy (AON) is an inherited neurological disorder. The Disease is characterised by progressive weakness that starts with the hind limbs leading to wobbly gait, wide-base stance and angled hocks. Symptoms typically begins between the age of 7.5 and 9 years.<!-- FIRST PARAGRAPH MARKER --></p> <h2>Test specific information</h2> <p>This test is performed by The University of Missouri Animal Molecular Genetic Lab</p> <h2>Age</h2> <p>&lsquo;Late onset&rsquo; &ndash; This phrase indicates, that the symptoms of the disease can be detected at a later ages. &lsquo;Late onset&rsquo; is the opposite of &lsquo;early onset&rsquo;, in which symptoms may be present at younger ages. The phrases are used because the mutation causing &acute;late onset&acute; symptoms may be different compared to the mutations causing &acute;early onset&acute; symptoms.</p> <h2>Turnaround time</h2> <p>The Turnaround Time (TAT) depends on various factors, such as the shipment time of your sample to the test location, the test method(s) and whether the tests are performed completely or partially by a Partner Lab or Patent owner.</p> <p>The TAT of tests performed at our facilities is normally 10 working days after receipt of the sample at the testing laboratory (VHL, VHP or Certagen). For tests performed by a Partner Laboratory (so-called &quot;partner lab test&quot;) or patent owner, the TAT is at least 20 working days after receipt of your sample. Because the shipment time to our Partner Labs or patent owner may vary due to factors we cannot influence, the mentioned 20 working days are therefore an estimate.</p> <p><strong>PLEASE NOTE</strong><br /> Sometimes it is necessary to re-run your sample. We call this a retest. In that case, the TAT will of course be extended.</p> <h2>Location of disease or trait</h2> <p>Trait or disease of brain and nervous system.</p> <h2>Breed dependence</h2> <p>This DNA test is available for the following breeds: Cocker Spaniel. Additional information is available in the Frequently Asked Questions (FAQ).</p> <h2>Sample type</h2> <p>For this DNA test we accept the following materials: Blood EDTA, Blood Heparin, Semen, Tissue, Swab. Please contact Dr. Van Haeringen Laboratorium if you wish to submit other material as listed.</p> <h2>Result</h2> <p>An animal can be free and has in that situation two healthy alleles. When used in breeding this animal will not become ill due to the disease. It cannot spread the disease in the population.<br /> <br /> An animal can be carrier and has in that situation one healthy and one disease allele. When used in breeding 50 percent of the offspring will receive the disease allele. Carriers will not become ill.<br /> <br /> An animal can be affected and has in that situation two disease alleles. When used in breeding all offspring will also receive the disease allele. Affected will become ill.</p> <h2>Inheritance</h2> <p>This genetic factor is inherited in an autosomal, recessive, mode. This means, that the individual can be free of the disease (homozygote normal), affected (homozygous affected) or carrier (heterozygous).<br /> <br /> Carriers may spread the mutation in a population without showing symptoms themselves. Because of this, it is extremely important to identify carriers correctly to prevent spreading of a mutation.</p> <h2>Severity of Disease</h2> <p>-</p> More information...
i H389 Alexander Disease Labrador Retriever € 50,18
A disease similar to human Alexander disease (AxD) was phenotypically described in several dog breeds, but the causal genetic variants were unknown. The disease is a fatal neurodegenerative disorder due to astrocyte dysfunction. The characteristic pathological feature are widespread and abundant astrocytic protein aggregates (Rosenthal fibers), which mainly consist of glial fibrillary acidic protein (GFAP). In humans, all genetic causes of AxD are mutations in GFAP, mostly dominant de novo variants arising from two mutation hotspots. In a Labrador Retriever with a juvenile form of the disease a GFAP mutation was identified, which is orthologous to a heterozygous de novo dominant hotspot variant, known to cause a severe phenotype in humans. More information...
i H351 Amelogenesis Imperfecta Greyhound, Italian Greyhound € 50,18
This disease is characterized by familial enamel hypoplasia. The condition uniformly affects deciduous and permanent teeth and is manifested by enamel roughening/thinning and brownish mottling. Affected teeth are often small and pointed with increased gaps. No tissues or organs other than teeth were affected by this mutation, and there was no relationship between enamel hypoplasia and either autoimmunity or periodontal disease, which also are prevalent in the breed. More information...
i H679 Amelogenesis Imperfecta 2 Parson Russel Terrier € 50,18
Amelogenesis imperfecta represents a heterogeneous group of inherited disorders affecting enamel development. The condition uniformly affects deciduous and permanent teeth and is manifested by enamel roughening/thinning and brownish mottling. Affected teeth are often small and pointed with increased gaps. No tissues or organs other than teeth are affected by this disease. AI can be classified in hypoplastic, hypomaturation and hypomineralized types. Mutations in different genes have been identified as likely causes of the disease. More information...
i H680 Amelogenesis Imperfecta 3 Akita € 50,18
Amelogenesis imperfecta represents a heterogeneous group of inherited disorders affecting enamel development. The condition uniformly affects deciduous and permanent teeth and is manifested by enamel roughening/thinning and brownish mottling. Affected teeth are often small and pointed with increased gaps. No tissues or organs other than teeth are affected by this disease. AI can be classified in hypoplastic, hypomaturation and hypomineralized types. Mutations in different genes have been identified as likely causes of the disease. More information...
i H450 Bleeding disorder due to P2RY12 defect Great Swiss Mountain Dog, Bichon Frise € 50,18
This genetic disease is caused by a defect in the gen identified as P2RY12. The symptoms are characterized as a severe bleeding disorder, often leading to postoperative hemorrhage. More information...
i H487 Brachyury (Bobtail) Welsh Corgi, Australian Shepherd, Jack Russell Terrier, Karelian Beardog, Polish Lowland Sheepdog (Polski Owczarek Nizinny - PON), Spanish Water Dog, Austrian Pinscher, Braque du Bourbonnais, Australian Stumpy Tail Cattle Dog, Brittany Spaniel, Croation Sheepdog (Hrvatski Ovcar), Mudi, Brazilian Terrier, Pyrenean Shepherd, Savoy Sheepdog, Swedisch Vallhund, Danish-Swedish Farmdog € 50,18
Dog tails are known in many variants. A common sort is a very short tail. Brachyury or bob-tail is the name given to the morphological appearance in which dogs have an extremely short or no tail. More information...
i H412 C3 Deficiency Brittany Spaniel € 50,18
The third component of complement (C3) plays a critical role in the generation of the inflammatory and protective functions of the complement system. C3 is also critical in the generation of the chemotactic and bactericidal activities of complement, hence C3 is critical to a functional immune system. More information...
i H749 Centronuclear Myopathy (CNM, also known as HMLR) Labrador Retriever € 50,18
Skeletal muscle myopathy is a hereditary muscle disorder in which there is a deficiency of type II muscle fibers leading to a notable decrease in skeletal muscle mass. Although several breeds of dogs have been observed to demonstrate similar disorders, this condition is only seen in Labrador retrievers and was first reported and described in 1976. In 1981, the same researchers characterized the mode of inheritance in Labradors and since that time the condition has been referred to as Hereditary Myopathy of Labrador Retrievers (HMLR). Other names for HMLR include muscular dystrophy, myotonia, generalized muscle weakness, polyneuropathy, and hereditary myopathy. More information...
i H413 Cerebellar Abiotrophy (NCCD) Beagle € 50,18
Puppies affected with CA appear normal at birth, but develop symptoms at a young age. As soon as six weeks after birth, the disease may cause the death of neurons in the cerebellum of affected foals. This leads to symptoms such as head tremor and a lack of balance equilibrium (ataxia). They tend to startle easily and often fall. In several cases, the neurological symptoms may not even be apparent to owners. Symptoms of CA vary in severity. More information...
i H410 Cerebellar Ataxia Coton de Tulear € 50,18
Neonatal Cerebellar Ataxia is a disease becomes apparent as soon as their littermates developed coordinated movements. The affected puppies exhibited intention tremors. Most were unable to walk, however righting reflexes were delayed. More information...
i H331 Cerebellar Ataxia (SDCA1) Belgian Shepherd € 50,18
Usually, heritable ataxia in dogs presents with a wide range of clinical symptoms, histopathologic findings and variable age of onset. The observed heterogeneity led to the assumption of different heritable forms of ataxia segregating in dogs. A mutation in KCNJ10 was identified as the cause of an autosomal recessive form called “spinocerebellar ataxia with myokymia, seizures or both” which affects various Terrier breeds. A second mutation in KCNJ10 was detected leading to a different form called “spongy degeneration with cerebellar ataxia, subtype 1” (SDCA1). The variant was exclusively found in Malinois dogs, a variety of the Belgian Shepherd breed and also showed an autosomal recessive form of inheritance. Hence, as not all affected Belgian Shepherd dogs presenting with neurological abnormalities were homozygous for that variant, more than one form of heritable ataxias must exist in the breed. More information...
i H804 Cerebellar Ataxia / NCL-A American Staffordshire Terrier (AmStaff) € 50,18
Cerebellar Ataxia/NCL-A (Neuronal Ceroid Lipofuscinoses) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H653 Cerebellar Ataxia 2 Old English Sheepdog, Gordon Setter € 50,18
The cerebellar ataxia is a serious neurological disease causing a degeneration of the nervous system. The disease usually appears between 3 and 5 years. Symptoms include tremors and a loss of balance. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H411 Cerebellar Ataxia, progressive early-onset Finnish Hound € 50,18
Puppies affected with CA appear normal at birth, but develop symptoms at a young age. As soon as six weeks after birth, the disease may cause the death of neurons in the cerebellum of affected foals. This leads to symptoms such as head tremor and a lack of balance equilibrium (ataxia). They tend to startle easily and often fall. In several cases, the neurological symptoms may not even be apparent to owners. Symptoms of CA vary in severity. More information...
i H318 Cerebellar Cortical Degeneration Magyar Vizsla € 50,18
Cerebellar cortical degeneration (CCD) refers to a heterogeneous group of diseases, which are caused by various mutations in different genes. It has been reported in several dog breeds and exhibits a wide range of age of onset and rate of progression between the breeds. A typical histopathological finding is a diffuse loss of Purkinje cells in the cerebellar cortex. In the Hungarian Vizsla breed, a recessively inherited mutation in the SNX14 gene was identified, which leads to absence of SNX14 protein in the cerebellum of CCD affected dogs. More information...
i H355 Cerebellar Hypoplasia Resembling Eurasier € 50,18
This disease is characterized by a non-progressive mild to moderate cerebellar ataxia. Some dogs also had tremors, proprioceptive deficits, nystagmus, ventral strabismus, and reduced or absent menace reflex. More information...
i H356 Chondrodysplasia, Disproportionate Short-Limbed Karelian Beardog, Norwegian Elkhound € 50,18
This disease is characterized by a disproportionate short stature dwarfism of varying severity. More information...
i H346 Chondrodystrophy and Intervertebral Disc Disease Basset, Beagle, Cardigen Welsh Corgi, Chihuahua, Coton de Tulear, Dachshund, French Bulldog, Maltese, Nova Scotia Duck Tolling Retriever, Pembroke Welsh Corgi, Miniature and Toy Poodle, Shih Tzu, American Cocker Spaniel, Cavalier King Charles Spaniel, Chesapeake Bay Retriever, English Springer Spaniel, Lhaso Apso, Pekingese, Bichon Frise, Dandie Dinmont Terrier, English Bulldog, American Bulldog € 50,18
Domestication of the dog resulted in a large diversity in size and shape of different dog breeds. A striking feature is limb length, because short limbs define many breeds. This phenotype is caused by impaired growth of the long bones (chondrodystrophy), and chondrodystrophic breeds are also prone to intervertebral disc disease (IVDD). A genetic study in Nova Scotia Duck Tolling Retrievers identified a mutation on canine chromosome 12, which is responsible for chondrodystrophy and susceptibility to Hansen’s type I IVDD in many dog breeds. More information...
i H709 CLAD, Type I Irish setter € 50,18
Canine Leukocyte Adhesion Deficiency (CLAD) is a fatal immunodeficiency disease found in several breeds. The condition is caused by mutation in a gene encoding a leucocyte surface molecule, leading to a dysfunction of the granulocytes. Because their healing capacities are impaired, the affected dogs show severe infections. They die early in life from multiple severe infections, even if treated with massive doses of antibiotics. More information...
i H484 CLAD, Type III German Shepherd, Belgian Shepherd, Dutch Shepherd Dog € 50,18
Canine Leukocyte Adhesion Deficiency (CLAD) is a fatal immunodeficiency disease found in several breeds. The condition is caused by mutation in a gene encoding a leucocyte surface molecule, leading to a dysfunction of the granulocytes. Because their healing capacities are impaired, the affected dogs show severe infections. They die early in life from multiple severe infections, even if treated with massive doses of antibiotics. More information...
i H344 Cleft Lip / Palate and Syndactyly (CLPS) Nova Scotia Duck Tolling Retriever € 50,18
A complex phenotype of cleft lip, cleft palate and syndactyly (CLPS) was observed in the Nova Scotia Duck Tolling Retriever (NSDTR) breed. A genetic study identified a mutation in the ADAMTS20 gene as the likely cause of the disease. This mutation was not found in any other breed tested so far, suggesting that it is private to the NSDTR breed. More information...
i H871 CMR1 (Canine Multifocal Retinopathy) Mastiffs, Australian Shepherd, Great Pyrenees, Cane Corso, Perro de Presa Canarios, Boerboel, Miniature American Sheperd, Bull Mastif € 50,18
The CMR test is a DNA-based test that diagnoses multi-focal retinopathy occurring in several breeds. Canine Multi-focal Retinopathy (CMR) is an eye disease which includes numerous distinct (i.e. multi-focal), roughly circular patches of elevated retina with accumulation of material that produces gray-tan-pink colored lesions. These lesions, looking somewhat like blisters, vary in location and size, although typically they are present in both eyes of the affected dog. Most dogs exhibit no noticeable problem with vision despite their abnormal appearing retinas. More information...
i H730 CMR2 (Canine Multifocal Retinopathy) Coton de Tulear, Mastiffs € 50,18
The CMR test is a DNA-based test that diagnoses multi-focal retinopathy occurring in several breeds. Canine Multi-focal Retinopathy (CMR) is an eye disease which includes numerous distinct (i.e. multi-focal), roughly circular patches of elevated retina with accumulation of material that produces gray-tan-pink colored lesions. These lesions, looking somewhat like blisters, vary in location and size, although typically they are present in both eyes of the affected dog. Most dogs exhibit no noticeable problem with vision despite their abnormal appearing retinas. More information...
i H705 Collie Eye Anomaly (CEA_CH, partnerlab) Border Collie, Bearded Collie, Hokkaido, Nova Scotia Duck Tolling Retriever, Rough Collies, Sheepdogs, Smooth Collies, Lancashire Heeler, Australian Shepherd, Kelpie, Jack Russell Terrier, Parson Russel Terrier, Lapponian Herder € 50,18
Collies share Collie Eye Anomaly (CEA) with several other breeds. CEA is technically known as Choroidal Hypoplasia (CH). It is an eye disorder that causes abnormal development of the choroid - an important layer of tissue under the retina of the eye. The primary problem is choroidal hypoplasia (CH). There is under-development (hypoplasia) of the eye tissue layer called the choroid. Since the choroid layer does not develop normally from the start, the primary abnormality can be diagnosed at a very young age. The symptoms and signs can vary greatly among affected dogs within one breed, between parent and offspring and even within a litter. This creates a difficult situation for the breeder. More information...
i H710 Collie Eye Anomaly (CEA_CH, patent owner Optigen) Sheepdogs, Lancashire Heeler, Nova Scotia Duck Tolling Retriever, Hokkaido, Bearded Collie, Border Collie, Rough Collies, Smooth Collies, Australian Shepherd, Kelpie, Jack Russell Terrier, Parson Russel Terrier, Lapponian Herder € 130,23
Collies share Collie Eye Anomaly (CEA) with several other breeds. CEA is technically known as Choroidal Hypoplasia (CH). It is an eye disorder that causes abnormal development of the choroid - an important layer of tissue under the retina of the eye. The primary problem is choroidal hypoplasia (CH). There is under-development (hypoplasia) of the eye tissue layer called the choroid. Since the choroid layer does not develop normally from the start, the primary abnormality can be diagnosed at a very young age. The symptoms and signs can vary greatly among affected dogs within one breed, between parent and offspring and even within a litter. This creates a difficult situation for the breeder. More information...
i H918 Cone Degeneration German Shorthaired Pointer € 50,18
Cone Degeneration Disease (CD) is a rare disease causing day blindness due to degeneration of the retinal cones. CD in affected dogs can be diagnosed in the early weeks of the life. The pups become day-blind and are photophobic – meaning that exposure to bright light is irritating or even painful. The pup will shun brightly-lit areas.

In contrast to PRA (Progressive Retinal Atrophy), which is the more common type of retinal disease in many dog breeds, CD does not affect night vision.
More information...
i H357 Cone Rod Dystrophy 1 (crd1) American Staffordshire Terrier (AmStaff), American Pit Bull Terrier € 50,18
Cone Rod Dysplasia (crd) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H358 Cone Rod Dystrophy 2 (crd2) American Staffordshire Terrier (AmStaff), American Pit Bull Terrier € 50,18
Cone Rod Dysplasia (crd) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H625 Congenital Cornification Disorder Labrador Retriever € 50,18
Genodermatoses are hereditary skin diseases which are caused by gene mutations. X-linked dominant and semi-dominant genodermatoses show a characteristic skin patterning in heterozygous females, which is due to the random X-inactivation. This results in a pattern of affected and healthy skin regions. Investigation of a Labrador Retriever, showing such characteristic skin lesions lead to the identification of a large deletion in the NSDHL gene. More information...
i H416 Congenital Hypothyroidism (CHG) 1 Spanish Water Dog € 50,18
Congenital hypothyroidism with goiter (CHG) is typically due to a defect of thyroid hormone synthesis (aka dyshormonogenesis). Thyroid peroxidase (TPO) is a multifunctional, heme-containing enzyme whose activity is required, and several inactivating TPO mutations causing CHG in humans and dogs have been described. More information...
i H485 Congenital Hypothyroidism (CHG) 2 Tenterfield Terrier € 50,18
Congenital hypothyroidism with goiter (CHG) is typically due to a defect of thyroid hormone synthesis (aka dyshormonogenesis). Thyroid peroxidase (TPO) is a multifunctional, heme-containing enzyme whose activity is required, and several inactivating TPO mutations causing CHG in humans and dogs have been described. More information...
i H488 Congenital Hypothyroidism (CHG) 3 Toy Fox Terrier, Rat Terrier € 50,18
Congenital hypothyroidism with goiter (CHG) is typically due to a defect of thyroid hormone synthesis (aka dyshormonogenesis). Thyroid peroxidase (TPO) is a multifunctional, heme-containing enzyme whose activity is required, and several inactivating TPO mutations causing CHG in humans and dogs have been described. More information...
i H339 Congenital Myasthenic Syndrome Labrador Retriever € 50,18
Congenital myasthenic syndromes (CMSs) are heterogeneous neuromuscular disorders characterized by skeletal muscle weakness caused by disruption of signal transmission across the neuromuscular junction (NMJ). Skeletal muscle contraction is stimulated by acetylcholine (ACh), and terminated by acetylcholinesterase (AChE). The collagenous tail of acetylcholinesterase is encoded by the gene COLQ. A mutation in exon 14 of the gene was found to be causative for CMS in a Labrador Retriever family. More information...
i H425 Congenital Myasthenic Syndrome Old Danish Pointer € 50,18
A neuromuscular transmission defect known as congenital myasthenic syndrome (CMS) has been observed dogs for decades. Affected dogs are able to run normally for 5–30 min after which they take shorter and shorter strides and eventually fall down with flexed fore- and hindlegs. After some minutes rest, they are able to walk and run again for variable periods of time before the signs reappear More information...
i H626 Congenital Myasthenic Syndrome 2 Jack Russell Terrier € 50,18
Congenital myasthenic syndrome (CMS) is a general term for a group of genetic diseases in animals which usually start early in life with muscle weakness and fatigue. Investigation of affected Jack Russell Terriers led to the identification of a homozygous mutation in the CHRNE gene which is supposed to be causative for the disease in this breed. More information...
i H701 Coppertoxicosis Bedlington Terrier € 50,18
Canine copper toxicosis (CT) is a recessive disorder of copper accumulation which results in severe liver disease in several dog breeds. Unless specific anti-copper treatment is instituted, most affected dogs die at three to seven years of age. More information...
i H312 Craniomandibular Osteopathy (CMO) Cairn Terrier, Scottish Terrier, American Staffordshire Terrier (AmStaff), Skye Terrier, Westhighland White Terrier € 50,18
Craniomandibular osteopathy (CMO) is found in Cairn terriers, Scottish terriers and West Highland White terriers and rarely in other breeds of dogs. The disease affects form and function of bones of the skull (tympanic bullae) and jaw (mandible). It is usually recognized at an age from 4 to 7 months when problems with chewing and eating occur. The jaw is bilaterally thickened and several bones become so large and tender that the mouth cannot be fully opened. A causal CMO mutation was identified which showed an autosomal dominant inheritance with incomplete penetrance. In the initial study, more than 57% of homozygous mutant dogs were affected with CMO. Homozygous mutant dogs therefore are classified as having a high risk to develop CMO. Dogs heterozygous for the mutation might also develop clinical signs; they are classified at low risk. More information...
i H856 crd3 Glen of Imaal Terrier € 111,17
crd3 is one of several cone rod dystrophies that have been recognized in multiple breeds of dogs. All forms of CRD are characterized by the initial loss of cones, the cells in the retina that are responsible for vision in bright light/daylight, followed by the degeneration of rods, the retinal cells that operate during night vision. Unlike another recently identified cone rod dystrophy, crd2, that causes blindness in American Pit Bull Terrier pups by one year of age, crd3 is typically a late-onset disease. Clinical symptoms of crd3 are usually not evident until adulthood has been reached. More information...
i H766 crd4-PRA (previously cord1-PRA) Miniature Longhaired Dachshund, English Springer Spaniel, Tibetian Terrier € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H728 CSNB (Congenital Stationary Night Blindness) Briard € 50,18
The CSNB test is a DNA-based test that provides a method to unequivocally identify Congenital Stationary Night Blindness, or CSNB. As an effect of the disease, affected dogs are suffering from night blindness, and may have weak vision during the day. The amount of deteriorated vision may differ largely between dogs. In addition to reduced vision, affected dogs also show abnormal electroretinogram (ERG). More information...
i H703 Cystinuria I - A - 1 Landseer, New Foundlander € 50,18
Cystinuria is an inherited disorder caused by a defect in the transport of cystine, an amino acid, in the kidney tubules. This defect has been linked to a gene called SLC3A1 in the Newfoundland breed. Normally, cystine that is filtered in the kidney is reabsorbed within the tubules, resulting in little cystine in the urine. Dogs with Cystinuria do not properly reabsorb cystine (and a few other amino acids) in the kidney tubules, causing the urine to contain abnormally high levels of cystine. Cystine is insoluble in neutral pH or acidic urine, so excess urinary cystine results in formation of cystine crystals, which in turn can lead to formation of cystine calculi (stones) in the kidney and/or bladder. Because males have long, narrow urethras compared to females, irritation and blockage by calculi is much more common in the male. Males with Cystinuria suffer repeated inflammations of the urinary tract and are at risk for urinary blockage, which can, if not treated promptly, lead to kidney failure, bladder rupture, and death. Cystinuria has been reported in many breeds (and mixed breeds) of dogs. More information...
i H644 Cystinuria, type II - A Australian Cattle Dog, Border Collie € 50,18
Cystinuria is an inherited disorder caused by a defect in the transport of cystine, an amino acid, in the kidney tubules. Normally, cystine that is filtered in the kidney is reabsorbed within the tubules, resulting in little cystine in the urine. Dogs with Cystinuria do not properly reabsorb cystine (and a few other amino acids) in the kidney tubules, causing the urine to contain abnormally high levels of cystine. Cystine is insoluble in neutral pH or acidic urine, so excess urinary cystine results in formation of cystine crystals, which in turn can lead to formation of cystine calculi (stones) in the kidney and/or bladder. Because males have long, narrow urethras compared to females, irritation and blockage by calculi is much more common in the male. Males with Cystinuria suffer repeated inflammations of the urinary tract and are at risk for urinary blockage, which can, if not treated promptly, lead to kidney failure, bladder rupture, and death. Cystinuria has been reported in many breeds (and mixed breeds) of dogs. More information...
i H643 Cystinuria, type II - A - 1 Labrador Retriever € 50,18
Cystinuria is an inherited disorder caused by a defect in the transport of cystine, an amino acid, in the kidney tubules. Normally, cystine that is filtered in the kidney is reabsorbed within the tubules, resulting in little cystine in the urine. Dogs with Cystinuria do not properly reabsorb cystine (and a few other amino acids) in the kidney tubules, causing the urine to contain abnormally high levels of cystine. Cystine is insoluble in neutral pH or acidic urine, so excess urinary cystine results in formation of cystine crystals, which in turn can lead to formation of cystine calculi (stones) in the kidney and/or bladder. Because males have long, narrow urethras compared to females, irritation and blockage by calculi is much more common in the male. Males with Cystinuria suffer repeated inflammations of the urinary tract and are at risk for urinary blockage, which can, if not treated promptly, lead to kidney failure, bladder rupture, and death. Cystinuria has been reported in many breeds (and mixed breeds) of dogs. More information...
i H645 Cystinuria, type II - B Miniature Pinscher € 50,18
Cystinuria is an inherited disorder caused by a defect in the transport of cystine, an amino acid, in the kidney tubules. Normally, cystine that is filtered in the kidney is reabsorbed within the tubules, resulting in little cystine in the urine. Dogs with Cystinuria do not properly reabsorb cystine (and a few other amino acids) in the kidney tubules, causing the urine to contain abnormally high levels of cystine. Cystine is insoluble in neutral pH or acidic urine, so excess urinary cystine results in formation of cystine crystals, which in turn can lead to formation of cystine calculi (stones) in the kidney and/or bladder. Because males have long, narrow urethras compared to females, irritation and blockage by calculi is much more common in the male. Males with Cystinuria suffer repeated inflammations of the urinary tract and are at risk for urinary blockage, which can, if not treated promptly, lead to kidney failure, bladder rupture, and death. Cystinuria has been reported in many breeds (and mixed breeds) of dogs. More information...
i H308 Degenerative Myelopathy 2 (DM2 Bernese mountain) Bernese Mountain Dog € 50,18
Canine Degenerative Myelopathy (DM) is a disease, which is first diagnosed later on in life, as late as after 8 years of age. The disease develops due to a slow degeneration of the neural system in the backbone, which results in progressive loss of function. The initial stages include paralysis of the legs. The disease is frequently found, which led research to identify two mutations in the SOD1-gene. More information...
i H673 Degenerative Myelopathy, DM (partner lab) All breeds € 50,18
Canine Degenerative Myelopathy (DM) is a disease which is first diagnosed later on in life, as late as after 8 years of age. The disease develops due to a slow degeneration of the neural system in the backbone, which results in progressive loss of function. The initial stages include paralysis of the legs.

The disease is frequently found, which led research to identify a mutation in the SOD1-gene.
More information...
i H806 Degenerative Myelopathy, DM (patent owner) All breeds € 113,71
Canine Degenerative Myelopathy (DM) is a disease which is first diagnosed later on in life, as late as after 8 years of age. The disease develops due to a slow degeneration of the neural system in the backbone, which results in progressive loss of function. The initial stages include paralysis of the legs.

The disease is frequently found, which led research to identify a mutation in the SOD1-gene.
More information...
i H327 Dental Hypomineralization (Raine Syndrome) Border Collie € 50,18
A developmental disorder of the teeth which is characterized by light brown discoloured and smooth enamel, extensive wear and inflammation is known in Border collies. The symptoms are caused by severe hypomineralization of the teeth of the affected dogs. A Next Generation Sequencing approach resulted in the identification of the causal mutation leading to the disease. The mutation is located in the FAM20C gene which plays an important role in cell differentiation and mineralization during tooth and bone development. The mode of inheritance is recessive. Genotyping of 20 dog breeds did not result in carrier identification, suggesting that the mutation is specific for Border Collies. More information...
i H489 Dermatofibrosis German Shepherd, Belgian Shepherd, Dutch Shepherd Dog € 50,18
Canine hereditary multifocal renal cystadeno carcinoma and nodular dermatofibrosis (RCND) is a naturally occurring inherited cancer syndrome in German Shepherd dogs. The syndrome is characterized by bilateral, multifocal tumors in kidneys and numerous firm nodules, consisting of dense collagen fibers in the skin and subcutis. More information...
i H434 Dilated Cardiomyopathy (DCM) Doberman Pinscher, Dobermann € 50,18
Dilated cardiomyopathy (DCM), the most common form of cardiomyopathy, often leads to heart failure and sudden death. More information...
i H635 Dilated Cardiomyopathy (DCM2) Doberman Pinscher € 50,18
Dilated cardiomyopathy (DCM), the most common form of cardiomyopathy, often leads to heart failure and sudden death. More information...
i H459 Dilated Cardiomyopathy (DCM3) Schnauzer € 50,18
Dilated cardiomyopathy (DCM), the most common form of cardiomyopathy, often leads to heart failure and sudden death. More information...
i H375 Dog_Skin Fragility Chesapeake Bay Retriever € 50,18
This disease is characterized by recurrent superficial skin sloughing and erosions at areas of friction and mucocutaneous junctions; the coat is finer than normal with patches of partial hair loss. Severe suprabasal acantholysis at birth, which became less severe with ageing. More information...
i H377 Dog_Spinal Dysraphism Weimaraner € 50,18
Spinal dysraphism is a broad term given to a group of anomalies where there are malformations in the dorsum of the embryo. More information...
i H739 Dominant PRA Bull Mastif, Mastiffs € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H913 Dry Eye Curly Coat Syndrome Cavalier King Charles Spaniel € 50,18
Dry Eye Curly Coat Syndrome is a congenital condition that affects the skin, eyes and nails. The syndrome is formally referred to as congenital keratoconjunctivitis sicca and ichthyosiform dermatosis (CKCSID).

This condition, which was first reported in the scientific literature in 2006, manifests at birth. Further clinical signs become evident in early life. Cases present with a congenitally abnormal (rough/curly) coat, signs of keratoconjunctivitis sicca (KCS) from eyelid opening, and are usually smaller than littermates. Also, reduced production of aqueous tears result in a tacky mucoid or mucopurulent ocular discharge and ulceration of the cornea in severe cases. Disease management is difficult.
More information...
i H385 Ectodermal Dysplasia X-linked German Shepherd € 50,18
A male German shepherd pup was described with symmetrical areas of hairlessness as well as missing and misshapen teeth. There was no family history of a similar phenotype. The symptoms resembled those in ectodermal dysplasia in the Tabby mouse and anhidrotic/hypohidrotic ectodermal dysplasia (HED) in man, which are both X-linked recessive disorders. The causative mutation in the dog was identified in the EDA gene which codes for ectodysplasin involved in the formation of hair follicles and tooth buds during fetal development. The mutation leads to a truncated protein and thus prevents correct function. More information...
i H497 Epidermolysis bullosa, dystrophic (RDEB) Golden Retriever € 50,18
Dystrophic Epidermolysis Bullosa is characterised by blister formation within the lamina lucida of the basement membrane zone. Clinical signs involve skin malformation resulting in blisters. Different areas of the body are affected. More information...
i H486 Epilepsy, BFJ Lagotto Romagnolo (Romagna Water Dog) € 50,18
Major remodeling of the neuronal synaptic network occurs during maturation of dogs. The amount of synapses formed in the brain manifolds during this time. In this remodeling phase errors may occur due to a genetic defect. This may lead to epilepsy on a very young age. More information...
i H674 Episodic Falling Disease (partner lab) Cavalier King Charles Spaniel € 50,18
Episodic falling (EF) IS also known as sudden collapse, muscle hypertonicity and hyperekplexia. The disease is usually induced by e.g. exercise or excitement. More information...
i H883 Episodic Falling Disease (patent owner) Cavalier King Charles Spaniel € 113,71
Episodic falling (EF) IS also known as sudden collapse, muscle hypertonicity and hyperekplexia. The disease is usually induced by e.g. exercise or excitement. More information...
i H672 Exercise Induced Collapse, EIC (partner lab) Labrador Retriever, Chesapeake Bay Retriever, Curly-Coated Retriever, Australian Labradoodle, Coton de Tulear, Parson Russel Terrier, Rhodesian Ridgeback, Australian Shepherd € 50,18
EIC (exercise-induced collapse) is a neuromuscular disorder, especially those dogs used for hunting and field trials. Research has identified the gene responsible for the condition known as EIC. A mutation in the canine dynamin 1 (DNM1) gene is very likely to be fundamentally responsible for EIC.

The syndrome of Exercise Induced Collapse (EIC) is manifested by muscle weakness and life-threatening collapse after intense exercise. Five to fifteen minutes of exercise causes dogs suffering from this condition to develop a wobbly gait, which soon progresses to a loss of control of the rear limbs. The symptoms may progress to all four limbs. Collapse episodes usually last for 10 minutes, and after 30 minutes there is often full recovery. The symptoms are occasionally fatal.
More information...
i H805 Exercise Induced Collapse, EIC (patent owner) Labrador Retriever, Chesapeake Bay Retriever, Curly-Coated Retriever, Australian Labradoodle, Coton de Tulear, Parson Russel Terrier, Rhodesian Ridgeback € 113,71
EIC (exercise-induced collapse) is a neuromuscular disorder, especially those dogs used for hunting and field trials. Research has identified the gene responsible for the condition known as EIC. A mutation in the canine dynamin 1 (DNM1) gene is very likely to be fundamentally responsible for EIC.

The syndrome of Exercise Induced Collapse (EIC) is manifested by muscle weakness and life-threatening collapse after intense exercise. Five to fifteen minutes of exercise causes dogs suffering from this condition to develop a wobbly gait, which soon progresses to a loss of control of the rear limbs. The symptoms may progress to all four limbs. Collapse episodes usually last for 10 minutes, and after 30 minutes there is often full recovery. The symptoms are occasionally fatal.
More information...
i H467 Exercise Induced Metabolic Myopathy German Hunt Terrier € 50,18
A phenotype of an inherited form of exercise induced metabolic myopathy was detected in German Hunting Terriers. Clinical signs in affected dogs are generalized weakness, exercise intolerance, severe diffuse muscle pain and a brownish discoloration of the urine after exercise. Pedigree analysis revealed an autosomal recessive mode of inheritance. A mutation in the ACADVL gene was identified as the most likely cause of the disease. More information...
i H607 Factor IX Deficiency Rhodesian Ridgeback € 50,18
Haemophilia B is an X-linked inherited disorder, which affects blood coagulation due to a lack of active coagulation factor IX. Bleeds can occur internally, into joints and muscles, or externally, from minor cuts or surgeries. The severity depends on how much active factor IX is present in the plasma. Different mutations in the gene encoding factor IX are known in different dog breeds. In Rhodesian Ridgebacks, a mutation was identified, which leads to a severe form of haemophilia B in this breed. More information...
i H435 Factor VII deficiency Beagle, Basset, Miniature Smoothhaired Dachshund, German Shorthaired Pointer, Whippet, English Foxhound, Harrier € 50,18
Hereditary factor VII (FVII) deficiency is characterized as a mild bleeding disorder. Factor VII is a vitamin K-dependent serine protease coagulation factor. It is synthesized in the liver and secreted into the circulation where it plays an important role in the initiation of coagulation. More information...
i H324 FBN2 All breeds € 50,18
Laxity of the hip joint is a frequent disorder in dogs. The disease is of multifactorial origin, which means that the symptoms are a combination of genetic factors as well as the environment.

Hip Laxity has two main characteristics:
• Laxity: This can be defined by ‘an abnormal freedom of movement of the bone in the hip joint’. As a result, the hip is less stable compared to healthy dogs.
• Ossification and bone formation. In younger dogs, the normal process of bone formation can be slowed down.

Both Laxity and Ossifcation disorders lead to the development of artrosis when dogs mature. Dogs which are affected most can already express symptoms after a few months. Other affected dogs develop artrosis at later ages.

This marker is part of a panel of genetic factors influencing hip laxity.
More information...
i H676 FN, Familial Nephropathy (partner lab) Cocker Spaniel € 50,18
The FN test is a DNA-based test that accurately diagnoses a fatal kidney disease . Familial Nephropathy (FN) has been referred to in several ways: kidney failure, fatal renal disease, juvenile nephropathy, renal cortical hypoplasia, hereditary nephritis (HN), Autosomal Hereditary Recessive Nephropathy (AHRN) in canines and Alports Syndrome in humans. FN disease is a juvenile-onset fatal kidney (renal) failure recognized for more than 50 years. The renal disease caused by FN invariably is progressive and ultimately fatal. More information...
i H729 FN, Familial Nephropathy (patent owner) Cocker Spaniel € 139,76
The FN test is a DNA-based test that accurately diagnoses a fatal kidney disease . Familial Nephropathy (FN) has been referred to in several ways: kidney failure, fatal renal disease, juvenile nephropathy, renal cortical hypoplasia, hereditary nephritis (HN), Autosomal Hereditary Recessive Nephropathy (AHRN) in canines and Alports Syndrome in humans. FN disease is a juvenile-onset fatal kidney (renal) failure recognized for more than 50 years. The renal disease caused by FN invariably is progressive and ultimately fatal. More information...
i H633 FN, Familial Nephropathy 2 English Springer Spaniel € 50,18
The FN test is a DNA-based test that accurately diagnoses a fatal kidney disease . Familial Nephropathy (FN) has been referred to in several ways: kidney failure, fatal renal disease, juvenile nephropathy, renal cortical hypoplasia, hereditary nephritis (HN), Autosomal Hereditary Recessive Nephropathy (AHRN) in canines and Alports Syndrome in humans. FN disease is a juvenile-onset fatal kidney (renal) failure recognized for more than 50 years. The renal disease caused by FN invariably is progressive and ultimately fatal. More information...
i H736 Fucosidosis English Springer Spaniel € 50,18
Fucosidosis is a lysosomal storage disorder caused by deficiency of the enzyme a-L-fucosidase. In an healthy animal, this enzyme cleaves complex proteins and lipids so that they can be metabolised. A diseased animal lacks this enzyme whereby the complex proteins and lipids are stored in diverse organs; for example in lymph nodes, pancreas, liver, kidneys, lungs and bone marrow and especially in cerebral and neural tissue. The disease in the Springer Spaniel manifests as a mainly neurological syndrome with mixed motor and mental function deficits. Affected animals show a disturbed coordination of movements, behavioural abnormalities, blindness, deafness and problems in deglutition. The disease occurs between the age of 18 months and 4 years with a progressive course and finally lethal outgoing. More information...
i H360 Gallbladder Mucocele Cairn Terrier, Cocker Spaniel, Wolfspitz, Sheltie, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 50,18
This disease is characterized by formation of gallbladder mucoceles (cysts). More information...
i H361 Gangliosidosis, GM2, Type I (B variant) Japanese Chin € 50,18
GM2 gangliosidosis, a lysosomal storage disease, is a recessive genetic disorder. It is caused by a lack of an enzyme that allows the build up of toxic substances in the nerve cells. The disorder is fatal to affected puppies. Affected dogs exhibit progressive cerebellar ataxia, altered mental status and vision deficits. The disease is progressive and leads to death or requires euthanasia within a few months. More information...
i H490 Gangliosidosis, GM2, type II Toy Poodle € 50,18
Storage Disease (GM2 gangliosidosis) is a recessive, genetic disorder. The disorder is caused by a lack of an enzyme that allows the build up of toxic substances in the nerve cells. It is fatal to affected puppies. More information...
i H496 Glaucoma (POAG) Beagle, East Siberian Laika € 50,18
Primary open angle glaucoma is a leading cause of blindness in dogs. Elevated intraocular pressure is the most important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown. More information...
i H737 Globoid Cell Leukodystrophy / Krabbes Disease Cairn Terrier, Westhighland White Terrier € 50,18
Globoid cell leukodystrophy or Krabbe disease is a severe, autosomal recessive dirsorder resulting from a deficiency of galactocerebrosidase (GALC) activity whereby the white matter is degenerated. Clinically, the symptoms appear between the 1st and 3rd months of age. Weakness of the limbs and tremors appear first, followed by muscular atrophy and neurological degeneration. The affected dogs may live until 8 or 9 months of age, when the symptoms become so severe that the dog is usually euthanized. Pathological studies of the white matter from affected dogs show characteristic globoid cells and loss of myelin. More information...
i H415 Glycogen Storage Disease GSD I Maltese € 50,18
Glycogen storage disease type I (GSD I) is an inherited abnormality of glucose metabolism. Normally, excess glucose is stored in many tissues as glycogen. If energy is needed, glucose molecules are removed from glycogen. The ability to add and remove glucose molecules from glycogen efficiently is dependent on its highly branched structure. The glycogen branching enzyme (GBE) is an enzyme of glycogen synthesis necessary to produce the branching structure. Deficiency of GBE activity leads to abnormal glycogen accumulation in myocytes, hepatocytes, and neurones, causing variably progressive, benign to lethal organ dysfunctions. More information...
i H702 GM1 Shiba Inu € 50,18
Storage Disease (GM1 gangliosidosis) is a recessive, genetic disorder. The disorder is caused by a lack of an enzyme that allows the build up of toxic substances in the nerve cells. It is fatal to affected puppies. More information...
i H472 Goniodysgenesis and glaucoma Border Collie € 62,89
Since the late 1990s, in Australian Border Collies a malformation of the anterior chamber of the eye (goniodysgenesis) in conjunction with a primary glaucoma was observed. Subsequently, the disease was also found in Europe and the USA. There are severe and mild forms of goniodysgenesis. The severe form seems to predispose the onset of glaucoma, but there are also dogs that do not develop glaucoma despite severe goniodysgenesis. Thus, other genetic or environmental factors must influence the development of glaucoma. In Border Collies, a mutation in the olfactomedin-like 3 gene (OLFML3) could be identified, which is most probably responsible for the development of the severe form of goniodysgenesis in homozygous animals. However, some heterozygous carriers of the mutation with different severe malformations of the anterior chamber but never with glaucoma were also found. It is therefore assumed that additional variants of other loci, so-called modifier loci, influence the development of goniodysgenesis. More information...
i H915 gPRA Schapendoes € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H868 GR_PRA1 Golden Retriever € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H473 GR_PRA2 Golden Retriever, Labrador Retriever € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. PRA is seen in many pure breeds, although the exact genetic cause is known for only a few. At present, about 10 genetic PRA forms are known to affect in several dozen of breeds. In some breeds, the DNA-test is 100 percent conclusive, but in other breeds the test is based on indirect information. Research is currently going on to improve the test. More information...
i H752 Gray Collie Syndrome (Cyclic Neutropenia) Collies € 50,18
Canine Cyclic Neutropenia is a stem cell disorder that occurs in collies. Puppies are usually smaller and weaker than their litter mates and by 8 to 12 weeks of age they develop clinical signs such as fever, diarrhea, joint pain, or other signs associated with eye, respiratory, or skin infections. The disorder is caused by an abnormality of the stem cells in the bone marrow, from which all blood cells are developed. The result is a cyclic fluctuation in blood cell numbers. Every 10 to 12 days the number of neutrophils drops dramatically, and then rebounds. The disease occurs in all gray (not merle) collies. More information...
i H347 GSDII (Pompe Disease) Finnish Lapphund, Lapponian Herder, Suomenlapinkoira € 50,18
Glycogen storage disease type II (GSD II), also called Pompe disease, is an inherited abnormality of glucose metabolism. Normally, excess glucose is stored in many tissues as glycogen. If energy is needed, glucose molecules are removed from glycogen. The ability to add and remove glucose molecules from glycogen efficiently is dependent on its highly branched structure. The enzyme alpha-glucosidase is needed to break down glycogen in lysosomes. Deficiency of this enzyme leads to storage of glycogen inside lysosomes and eventually also to cytoplasmic glycogen storage. Ultimately, the accumulation of glycogen results in tissue destruction. More information...
i H491 Haemophilia A (Factor VIII) (partner lab) German Shepherd, Belgian Shepherd, Dutch Shepherd Dog € 50,18
Haemophilia A is a coagulation disorder caused by defects in the large and complex coagulation factor VIII (FVIII) gene. The bleeding predisposition associated with haemophilia A results from a deficiency or dysfunction of FVIII, with the severity depending on the amount of residual FVIII activity. More information...
i H436 Haemophilia A (Factor VIII) (patent owner) German Shepherd € 113,71
Haemophilia A is a coagulation disorder caused by defects in the large and complex coagulation factor VIII (FVIII) gene. The bleeding predisposition associated with haemophilia A results from a deficiency or dysfunction of FVIII, with the severity depending on the amount of residual FVIII activity. More information...
i H392 Hemorragic diathesis (Scott Syndrome) German Shepherd € 50,18
Platelets, also called thrombocytes, play an important role in blood coagulation. They adhere to the surrounding tissue ("thrombocyte adhesion") or stick together ("thrombocyte aggregation"), so that the blood vessel injury is occluded. TMEM16F is an important member of this pathway, because it mediates the release of clot-promoting substances. Impairment of TMEM16F function leads to a rare bleeding disorder, which is called canine Scott Syndrome (CSS). It was discovered in German Shepherd dogs. CSS is inherited as an autosomal recessive disorder. The causative mutation is a splice site mutation in the ANO6 gene. More information...
i H809 Hereditary Cataract (HC) - HSF4 Australian Shepherd, Bull Terrier, French Bulldog, American Bulldog, English Bulldog € 50,18
Hereditary Cataract (HC) is frequently described as a ‘Grey Star’. HC is one of the common reasons for blindness in dogs. Symptoms may already appear at young ages, while the progressive disease becomes worse leading to complete blindness later in life. The only available cure currently is surgery.

Research has discovered a mutation in the HSF4 gene, which has been described in scientific literature as the causative mutation for HC.
More information...
i H699 Hereditary Cataract 2 (HSF4) Staffordshire Bull Terrier, Boston Terrier, French Bulldog € 50,18
Hereditary Cataract (HC) is frequently described as a ‘Grey Star’. HC is one of the common reasons for blindness in dogs. Symptoms may already appear at young ages, while the progressive disease becomes worse leading to complete blindness later in life. The only available cure currently is surgery.

Research has discovered a mutation in the HSF4 gene, which has been described in scientific literature as the causative mutation for HC.
More information...
i H919 Hiplaxity 1 All breeds € 50,18
Laxity of the hip joint is a frequent disorder in dogs. The disease is of multifactorial origin, which means that the symptoms are a combination of genetic factors as well as the environment.

Hip Laxity has two main characteristics:
• Laxity: This can be defined by ‘an abnormal freedom of movement of the bone in the hip joint’. As a result, the hip is less stable compared to healthy dogs.
• Ossification and bone formation. In younger dogs, the normal process of bone formation can be slowed down.

Both Laxity and Ossifcation disorders lead to the development of artrosis when dogs mature. Dogs which are affected most can already express symptoms after a few months. Other affected dogs develop artrosis at later ages.

This marker is part of a panel of genetic factors influencing hip laxity.
More information...
i H421 Hiplaxity 2 All breeds € 50,18
Laxity of the hip joint is a frequent disorder in dogs. The disease is of multifactorial origin, which means that the symptoms are a combination of genetic factors as well as the environment.

Hip Laxity has two main characteristics:
• Laxity: This can be defined by ‘an abnormal freedom of movement of the bone in the hip joint’. As a result, the hip is less stable compared to healthy dogs.
• Ossification and bone formation. In younger dogs, the normal process of bone formation can be slowed down.

Both Laxity and Ossifcation disorders lead to the development of artrosis when dogs mature. Dogs which are affected most can already express symptoms after a few months. Other affected dogs develop artrosis at later ages.

This marker is part of a panel of genetic factors influencing hip laxity.
More information...
i H675 HNPK (partner lab) Labrador Retriever € 50,18
Hereditary nasal parakeratosis (HNPK) is part of the group of diseases identified as genodermatosis. Affected dogs develop crusts and fissuring of the nasal planum at a young age but are otherwise healthy. More information...
i H443 HNPK (patent owner) Labrador Retriever € 139,12
Hereditary nasal parakeratosis (HNPK) is part of the group of diseases identified as genodermatosis. Affected dogs develop crusts and fissuring of the nasal planum at a young age but are otherwise healthy. More information...
i H363 Hyperkeratosis, epidermolytic Norfolk Terrier € 50,18
Hyperkeratosis is a skin disorder characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop skin lesions as a result of (unknown) other mutations. More information...
i H492 Hyperkeratosis, palmoplantar Irish Terrier, Kromfohrländer, Bedlington Terrier, Welsh Terrier € 50,18
Hyperkeratosis is a skin disorder characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop skin lesions as a result of (unknown) other mutations. More information...
i H811 Hyperuricemia (HUU) All breeds € 50,18
The disease results from inefficient transport of uric acid in both the liver and kidney, which leads to elevated levels of uric acid in blood and urine and can result in significant diseases with the names Hyperuricosuria or Hyperuricemia (HUU).

Research has discovered a mutation in the SLC2A9 gene, which has been described in scientific literature as the causative mutation for HUU.
More information...
i H364 Hypocatalasia Beagle, Miniature and Toy Poodle, English Foxhound, Harrier € 50,18
This disease is characterized by genetic deficiency of catalase activity in erythrocytes. More information...
i H365 Hypomyelination Weimaraner € 50,18
A hypomyelination syndrome is a disease characterised by a reduction or absence of myelin in the axons of the central nervous system (CNS) exclusively. This myelination disruption results in a notable tremor syndrome from which affected dogs recover with time. More information...
i H636 Hypophosphatasia Karelian Beardog € 50,18
Inherited skeletal disorders are a group of conditions that affect the bone and cartilage tissues. One of these conditions is called hypophosphatasia (HPP). Human HPP is a metabolic bone disease which is characterized by impaired skeletal mineralization and caused by mutations in the alkaline phosphatase gene (ALPL). A study conducted on Karelian Bear Dogs presenting symptoms resembling the human infantile form of HPP identified a recessive mutation in the canine ALPL gene which most likely is a causative variant leading to HPP in this breed. More information...
i H873 Ichthyosis 2 Golden Retriever, Goldendoodle, Rhodesian Ridgeback € 50,18
Ichthyosis is not one but rather a group of skin disorders characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop ichthyosis as a result of (unknown) other mutations. More information...
i H304 Ichthyosis 3 Great Dane € 50,18
Ichthyosis is not one but rather a group of skin disorders characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop ichthyosis as a result of (unknown) other mutations. More information...
i H378 Ichthyosis 4 American Bulldog, English Bulldog, French Bulldog € 50,18
Ichthyosis is not one but rather a group of skin disorders characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop ichthyosis as a result of (unknown) other mutations. More information...
i H384 Ichthyosis 5 German Shepherd € 50,18
Ichthyosis is not one but rather a group of skin disorders characterized by noninflammatory scaling of the skin. Many different metaphors have been used to describe the appearance and texture of the skin in the various types and stages of ichthyosis, for example fish skin. This test detects only one mutation. Therefore a dog can still develop ichthyosis as a result of (unknown) other mutations. More information...
i H366 IGS (Selective Cobalamin Malabsorption) 1 Beagle € 50,18
Vitamin B12 malabsorbtion is a serious and potentially life-threatening metabolic disease in puppies and young dogs. In affected dogs, the lining of the lower intestine will not absorb vitamin B12. The disease can cause a wide range of clinical problems, including lack of appetite, lethargy, failure to thrive, wasting, vomiting, seizures, or general ill-health. The most serious complications include abnormalities of the blood and nervous system that are lethal if untreated. Fortunately, with proper diagnosis and relatively inexpensive treatment, affected dogs can be kept in remission throughout their lives. More information...
i H367 IGS (Selective Cobalamin Malabsorption) 2 Border Collie, Bearded Collie, Rough Collies, Smooth Collies € 50,18
Vitamin B12 malabsorbtion is a serious and potentially life-threatening metabolic disease in puppies and young dogs. In affected dogs, the lining of the lower intestine will not absorb vitamin B12. The disease can cause a wide range of clinical problems, including lack of appetite, lethargy, failure to thrive, wasting, vomiting, seizures, or general ill-health. The most serious complications include abnormalities of the blood and nervous system that are lethal if untreated. Fortunately, with proper diagnosis and relatively inexpensive treatment, affected dogs can be kept in remission throughout their lives. More information...
i H332 IGS (Selective Cobalamin Malabsorption) 3 Australian Shepherd € 50,18
Vitamin B12 malabsorbtion is a serious and potentially life-threatening metabolic disease in puppies and young dogs. In affected dogs, the lining of the lower intestine will not absorb vitamin B12. The disease can cause a wide range of clinical problems, including lack of appetite, lethargy, failure to thrive, wasting, vomiting, seizures, or general ill-health. The most serious complications include abnormalities of the blood and nervous system that are lethal if untreated. Fortunately, with proper diagnosis and relatively inexpensive treatment, affected dogs can be kept in remission throughout their lives. More information...
i H335 Juveniele Myoclonic Epilepsy Rhodesian Ridgeback € 50,18
Epilepsy is a common chronic neurological disease in dogs. In Rhodesian Ridgebacks, an early onset myoclonic epilepsy with photosensitivity was described. First symptoms became visible between 6 weeks and 18 month of age and in a considerable number of cases visually induced seizures were reported. A causal mutation was identified in the DIRAS1 gene which is expressed in CNS tissues. Although the biological function of the protein is poorly characterized to date, a role in acetylcholine release regulation and nervous system development is assumed. More information...
i H329 Juvenile Laryngeal Paralysis Polyneuropathy (JLPP) Black Russian Terrier, Rottweiler € 50,18
A juvenile-onset laryngeal paralysis and polyneuropathy was reported in Black Russian Terriers (BRT). Clinical signs included respiratory distress due to laryngeal paralysis and gait abnormalities progressing to a severe ataxia. Further examinations of additional affected BRT led to an extended disease description which includes polyneuropathy with ocular abnormalities and neuronal vacuolation (POANV). The causal mutation of the disease in the BRT breed was identified in the RAB3GAP1 gene. This gene plays an important role in the development of a variety of membrane structures and thus impairment of the biological function leads to heterogeneous clinical symptoms. More information...
i H724 L2-HGA Staffordshire Bull Terrier € 50,18
L2-HGA is the abbreviation for L2-Hydroxyglutaric aciduria. Because symptoms may vary a lot, this disease may be confused with other (frequent) diseases. The disease is recognized by e.g. attacks of epilepsy, muscle coordination, stiffness of muscles during movement and atypical behaviour (staring at walls, hiding in corners or under tables, loss of control). More information...
i H468 Lafora disease Beagle, Miniature Wirehaired Dachshund € 95,29
Lafora disease (LD) is an autosomal recessive late onset, progressive myoclonic epilepsy (PME). It is characterized by intracellular accumulation of abnormal glycogen (Lafora bodies). Most common clinical signs are myoclonus and generalized seizures. The causative mutation was detected in the NHLRC1 gene. The normal sequence contains nearly identical dodecamers which can be present in two or three copies. In affected dogs, both alleles are expanded with 19 to 26 copies of the dodecamer sequence. More information...
i H463 Lethal Acrodermatitis (LAD) Bull Terrier, Miniature Bull Terrier € 50,18
Lethal acrodermatitis (LAD) is inherited as a monogenic autosomal recessive trait in Bull Terriers and Miniature Bull Terriers. Affected dogs grow poorly, are immunodeficient and suffer from skin lesions, especially on the paws. LAD symptoms become apparent in the first weeks of life. Due to severe infections, affected dogs die early or are euthanized. A variant in the MKLN1 gene, which encodes the protein muskelin 1 was identified as cause of the disease. More information...
i H395 Limb girdle muscular dystrophy (LGMD) 1 Boston Terrier € 50,18
Limb girdle muscular dystrophies (LGMD) are a heterogeneous group of disorders, which mainly affect muscles of the shoulders and hips, but heart and respiratory muscles can also be involved. Clinical signs are marked muscle weakness and atrophy in the shoulder and hips. A group of severe, recessive LGMDs are the Sarcoglycanopathies. They are caused by mutations in one of the six known sarcoglycan genes and result in sarcoglycan deficiency. In Boston terriers, two deletions in SGCD where identified as the cause of the disease. More information...
i H317 Macular Corneal Dystrophy Labrador Retriever € 50,18
Macular corneal dystrophy (MCD) is a rare hereditary disease that occurs in Labrador Retrievers. Due to accumulation of glycosaminoglycans, progressive clouding of the cornea is observed in affected individuals. A study conducted with dogs of this breed identified a causal mutation in the canine carbohydrate sulfotransferase-6 (CHST6) gene. The disease is inherited as a recessive condition and can cause visual impairment in affected dogs. More information...
i H746 Maligne Hyperthermia All breeds € 50,18
Maligant hyperthermia (MH) is an inherited disorder of skeletal muscle characterized by hypercarbia, rhabdomyolysis, generalized skeletal muscle contracture, cardiac dysrhythmia, and renal failure, that develops on exposure to succinylcholine or volatile anesthetic agents. Specific interventions, including use of the calcium release channel antagonist dantrolene, are efficacious in reversing signs of the canine syndrome. More information...
i H629 MDR1 (partner lab) All breeds € 50,18
The Multidrug Resistance gene 1 (the MDR1 gene) plays an important role in the barrier between blood capillaries and brain tissue. Dogs suffering from oversensitivity for Ivermectine have been documented to be susceptible to neurotoxicity induced by many other drugs as well. More information...
i H631 Microphtalmia € 50,18
Microphthalmia belongs to a group of congenital eye malformations. In Irish soft-coated wheaten terriers (ISCWTs), an amino acid deletion in the retinol-binding protein 4 (RBP4) was identified as cause of the disease. Normal RBP4 carries vitamin A from hepatic stores to peripheral tissues, including the placenta and eye. There it is used as substrate for synthesis of retinoic acid, an important molecule for proper tissue development. The mutation disrupts folding of the retinol-binding protein which decreases its secretion from hepatocytes to serum, resulting in gestational vitamin A deficiency. The eye is most sensitive to impaired synthesis of retinoic acid among organs and vitamin A deficiency is a known risk factor for ocular birth defects. Inheritance of the disease is unusual. It is an autosomal recessive trait, but it is only expressed, when both dam and offspring are deletion homozygotes. Normal RBP carries vitamin A to and from cells of the materno-fetal interface. Only if maternal and fetal RBP4 mutations are homozygous, the vitamin A level is reduced below the threshold for expression of the disease in the offspring. More information...
i H427 MTM Labrador Retriever € 50,18
Myotubular myopathy is a disease characterized by early onset and the presence of uniformly small muscle fibers with centrally placed nuclei resembling fetal myotubes. Onset of clinical signs is typically at or near birth, and affected males have profound hypotonia and weakness accompanied by respiratory difficulties. More information...
i H451 Mucopolysaccharidose Type VII - 2 Brazilian Terrier € 50,18
Mucopolysaccharidosis belongs to a group of genetic disorders of glycosaminglycan catabolism resulting in lysosomal storage. Clinical signs are corneal clouding and severe skeletal deformities. Affected dogs are unable to ambulate at several weeks to months of age. More information...
i H418 Mucopolysaccharidosis Type IIIa Dachshund € 50,18
Mucopolysaccharidosis belongs to a group of genetic disorders of glycosaminglycan catabolism resulting in lysosomal storage. Clinical signs are corneal clouding and severe skeletal deformities. Affected dogs are unable to ambulate at several weeks to months of age. More information...
i H748 Mucopolysaccharidosis Type VII German Shepherd, Belgian Shepherd, Dutch Shepherd Dog € 50,18
Mucopolysaccharidosis type VII belongs to a group of rare genetic disorders of glycosaminglycan catabolism resulting in lysosomal storage. Clinical signs are corneal clouding and severe skeletal deformities. Affected dogs are unable to ambulate at several weeks to months of age. More information...
i H306 Multifocal Retinopathy 3 (cmr3) 1 Lapponian Herder, Suomenlapinkoira € 50,18
The CMR test is a DNA-based test that diagnoses multi-focal retinopathy occurring in several breeds. Canine Multi-focal Retinopathy (CMR) is an eye disease which includes numerous distinct (i.e. multi-focal), roughly circular patches of elevated retina with accumulation of material that produces gray-tan-pink colored lesions. These lesions, looking somewhat like blisters, vary in location and size, although typically they are present in both eyes of the affected dog. Most dogs exhibit no noticeable problem with vision despite their abnormal appearing retinas. More information...
i H307 Multifocal Retinopathy 3 (cmr3) 2 Lapponian Herder, Suomenlapinkoira € 50,18
The CMR test is a DNA-based test that diagnoses multi-focal retinopathy occurring in several breeds. Canine Multi-focal Retinopathy (CMR) is an eye disease which includes numerous distinct (i.e. multi-focal), roughly circular patches of elevated retina with accumulation of material that produces gray-tan-pink colored lesions. These lesions, looking somewhat like blisters, vary in location and size, although typically they are present in both eyes of the affected dog. Most dogs exhibit no noticeable problem with vision despite their abnormal appearing retinas. More information...
i H747 Muscular Dystrophy (GRMD) Golden Retriever € 50,18
Golden Retriever muscular dystrophy (GRMD) is a spontaneous, X-linked, progressively fatal disease of dogs and is also a homologue of Duchenne muscular dystrophy (DMD). Affected dogs show raised creatine kinase levels, muscle atrophy with contractures, hyaline myofiber degeneration with mineralization, endomysial and perimysial fibrosis with fatty infiltration, and cardiomyopathy. More information...
i H359 Muscular Dystrophy, Duchenne Type (DMD) Cavalier King Charles Spaniel € 50,18
This disease is characterized by sarcolemma dysfunction, which results in an increased intracellular calcium level and muscle fiber hypercontraction. Subsequent muscle fiber degeneration and necrosis. Eventually, muscle fibrosis, mineralization and fat infiltration occur in both skeletal and cardiac muscle. Lesions occur in cardiac muscle, usually occur after 6 months of age. More information...
i H419 Muscular Dystrophy, Duchenne type (MDM) Welsh Corgi € 50,18
Duchenne muscular dystrophy (DMD) is a dystrophin-deficient lethal muscle disease. The catastrophic muscle wasting phenotype has been seen in dystrophin-deficient humans and dogs. Duchenne-like symptoms have been observed in many dog breeds. More information...
i H493 Muscular hypertrophy (double muscling) Whippet € 50,18
The genetic variant results in an abnormal increase in muscular tisssue, caused entirily by enlargement of existing muscle cells. This is in contrast with muscular hyperplasia, in which the abnormal muscular size is caused by an increase in the number of muscle cells More information...
i H424 Musladin-Lueke syndrome (MLS) Beagle € 50,18
Musladin-Lueke Syndrome (MLS) is a hereditary disorder affecting dogs that manifests with extensive fibrosis of the skin and joints. In this respect, it resembles human stiff skin syndrome and the Tight skin mouse, each of which is caused by gene defects affecting fibrillin. More information...
i H391 Myasthenia gravis-like disease Heideterrier € 50,18
Congenital myasthenic syndrome (CMS) is a general term for a group of genetic diseases in animals which usually start early in life with muscle weakness and fatigue. Investigation of an affected Heideterrier led to the identification of a homozygous mutation in the CHRNE gene which is supposed to be causative for the disease in this dog. More information...
i H368 Myopathy Great Dane € 50,18
"The canine Inherited Myopathy of Great Danes (IMGD) is characterized by rapidly progressive muscle atrophy and exercise intolerance with an age of onset of about 6 months. Histological examinations of muscle biopsies from autosomal recessive cases from the UK, Canada and Australia revealed increased nuclear internalization and centralization, consistent with centronuclear myopathy. " More information...
i H738 Myotonia Congenita Miniature Schnauzer € 62,89
Myotonia congenita is a hereditary pathogenic condition affecting skeletal muscle ion channels and is characterized by a delay of relaxation ot the skeletal muscles following an electical or mechanical stimulus or after cessation of voluntary activity. Myotonia congenita results from genetic defects in the skeletal muscle chloride ion channel and the ensuing reduced chloride ion conductance across the sarcolemma. Myotonic Miniature Schnauzers have hypertrophic skeletal muscles, difficulty in rising after a period of rest, a stiff and stilted gait when walking, and a bunnyhop type movement when running. In addition, there are increased respiratory sounds, difficulty when swalling, ptyalism, dental abnormalities and superior prognathism. More information...
i H498 Myotonia Congenita 2 Australian Cattle Dog € 50,18
Myotonia congenita is a hereditary pathogenic condition affecting skeletal muscle ion channels and is characterized by a delay of relaxation of the skeletal muscles following an electrical or mechanical stimulus or after cessation of voluntary activity. Myotonia congenita results from genetic defects in the skeletal muscle chloride ion channel and the ensuing reduced chloride ion conductance across the sarcolemma. Myotonic Miniature Schnauzers have hypertrophic skeletal muscles, difficulty in rising after a period of rest, a stiff and stilted gait when walking, and a bunnyhop type movement when running. In addition, there are increased respiratory sounds, difficulty when swalling, ptyalism, dental abnormalities and superior prognathism. More information...
i H707 Narcolepsy 1 Dachshund € 50,18
Narcolepsy can be tested in several breeds. The disease is recognized by a frequent sleep of affected dogs. Dogs turn to a different sleeping pattern, and fall asleep unexpectedly. The disease may also be recognized by the Rapid Eye Movements (REM) during unexpected sleep. More information...
i H697 Narcolepsy 2 Doberman Pinscher, Dobermann € 50,18
Narcolepsy can be tested in several breeds. The disease is recognized by a frequent sleep of affected dogs. Dogs turn to a different sleeping pattern, and fall asleep unexpectedly. The disease may also be recognized by the Rapid Eye Movements (REM) during unexpected sleep. More information...
i H698 Narcolepsy 3 Labrador Retriever € 50,18
Narcolepsy can be tested in several breeds. The disease is recognized by a frequent sleep of affected dogs. Dogs turn to a different sleeping pattern, and fall asleep unexpectedly. The disease may also be recognized by the Rapid Eye Movements (REM) during unexpected sleep. More information...
i H460 Nasal parakeratosis Greyhound € 50,18
Hereditary nasal parakeratosis (HNPK) is part of the group of diseases identified as genodermatosis. Affected dogs develop crusts and fissuring of the nasal planum at a young age but are otherwise healthy. More information...
i H812 Neonatal Encephalopathy Poodle € 50,18
A neonatal encephalopathy with seizures has been linked to a mutation in the ATF2-gene. Affected puppies are small and weak at birth. Many die in their first week of life. Those surviving past one week develop wholebody tremor. By four to six weeks of age, the disease intensifies leading to death. More information...
i H370 Nephritis Samoyed € 50,18
Affected males develop renal failure as a result of a high protein concentration in the kidneys. More information...
i H428 Neuroaxonal Dystrophy Giant Schnauzer € 50,18
Neuroaxonal dystrophy (NAD) is a neurodegenerative pathology of the central and/or peripheral nervous system characterized by local swellings (spheroids) and atrophy of axons. Onset of signs is typically between 6 and 18 months of age and follows a progressive course of cognitive and motor regression and hypotonia. More information...
i H462 Neuroaxonal Dystrophy (Spanish Water Dog) Spanish Water Dog € 50,18
Neuroaxonal dystrophy (NAD) is a neurodegenerative pathology of the central and/or peripheral nervous system characterized by local swellings (spheroids) and atrophy of axons. Onset of signs is typically between 6 and 18 months of age and follows a progressive course of cognitive and motor regression and hypotonia. More information...
i H494 Neuronal ceroid lipofuscinosis (NCL) 1 Dachshund € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H429 Neuronal ceroid lipofuscinosis (NCL) 10 American Bulldog, English Bulldog, French Bulldog € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H458 Neuronal ceroid lipofuscinosis (NCL) 12 Tibetian Terrier € 50,18
Neuronal ceroid lipofuscinosis (NCL) is the generic term for neurodegenerative diseases that are based on an excessive accumulation of lipopigments (lipofuscin) in the tissue. These are waxy waste products of cell metabolism that are deposited in the skin, muscles, nerve cells, the retina and many other tissues. The associated damage to the retina can lead to blindness, while the storage of ceroid lipofuscin in nerve cells affects their function and causes a progressive degeneration of the nervous system. In Tibetan terriers, a late onset lethal form of NCL could be traced back to a mutation in the ATP13A2 gene. More information...
i H499 Neuronal ceroid lipofuscinosis (NCL) 2 Dachshund € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H721 Neuronal ceroid lipofuscinosis (NCL) 5 Border Collie, Rough Collies, Smooth Collies, Bearded Collie € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H380 Neuronal ceroid lipofuscinosis (NCL) 5 GR Golden Retriever € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H330 Neuronal ceroid lipofuscinosis (NCL) 6 Australian Shepherd € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H652 Neuronal ceroid lipofuscinosis (NCL) 8-1 English Setter, Irish setter, Gordon Setter € 50,18
Neuronal Ceroid Lipofuscinoses (CL) is a serious neurological disorder causing a degeneration of the central nervous system. The disease is caused by improper storage of energy in elements of cells (lysosomes). The disease usually appears between 3 and 5 years and includes tremors and a loss of balanced. The disease progresses slowly, the dog finding it increasingly difficult to walk. In the final stages, the dog is no longer able to move. More information...
i H337 Neuronal ceroid lipofuscinosis (NCL) 8-2 Australian Shepherd, Australian Cattle Dog € 50,18
Neuronal Ceroid Lipofuscinosis (NCL) is the umbrella term for neurodegenerative diseases due to an excessive accumulation of lipoproteins (lipofuscin) in the tissue. These are waxy waste products of the cell metabolism, which are deposited in the skin, muscles, nerve cells, the retina and many other tissues. The associated damage to the retina can lead to blindness, while the storage of the ceroid lipofuscins in nerve cells impairs their function and a progressive degeneration of the nervous system occurs. More information...
i H393 Oculocutaneous Albinism Bull Mastif € 50,18
Impairment of eumelanin and phaeomelanin synthesis leads to a reduction of pigmentation in skin hair and eyes. Mutations in six different genes have been identified to cause several distinct forms of oculocutaneous albinism in humans and many animal species. Variants in the SLC45A2 gene cause oculocutaneous albinism type 4 (OCA4). In a Bullmastiff, a deletion in exon 6 of SLC45A2 was identified as the likely cause of OCA. More information...
i H430 Osteogenesis imperfecta Beagle € 50,18
Osteogenesis Imperfecta are usually caused by a mutation in genes encoding collagen. Incomplete collagen results in various bone abnormalities in including brittle bone structure. More information...
i H431 Osteogenesis imperfecta 2 Dachshund € 50,18
Osteogenesis Imperfecta are usually caused by a mutation in genes encoding collagen. Incomplete collagen results in various bone abnormalities in including brittle bone structure. More information...
i H381 Osteogenesis Imperfecta 3 Golden Retriever € 50,18
Osteogenesis Imperfecta are usually caused by a mutation in genes encoding collagen. Incomplete collagen results in various bone abnormalities in including brittle bone structure. More information...
i H444 Palmoplantar keratoderma 1 (FNEPPK1) Dogue de Bordeaux € 50,18
In the Dogue de Bordeaux breed a hyperkeratosis mainly affecting the footpads was described. Affected dogs show thickening of the footpads, severe keratinous proliferations and fissures which increase the susceptibility to secondary infections. The disorder is inherited as an autosomal recessive trait with onset of symptoms between 10 weeks and 1 year of age. A genetic study identified a complex mutation in the KRT16 gene as cause for the disease. The mutation leads to a truncated protein and impairs normal keratin assembly. More information...
i H348 PAP-PRA1 Papillion, Phalene, Griffon Bruxellois € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H634 Paroxysmal Dyskinesia Soft-Coated Wheaten Terrier € 50,18
Hereditary paroxysmal dyskinesias (PxD) are a heterogeneous group of diseases characterized by episodes of abnormal involuntary movements. Canine PxDs usually have a recessive mode of inheritance. A young-adult onset form of the disease is known in Soft-Coated Wheaten Terriers. The episodes of hyperkinesia and dystonia last from several minutes to several hours and can occur more than 10 times a day. They were not associated with strenuous exercise or fasting but were sometimes triggered by excitement. A mutation in the PIGN gene was identified as cause of the disease in this breed. More information...
i H717 PFK (Phosphofructokinase Deficiency) Cavalier King Charles Spaniel, Cocker Spaniel, Tibet Spaniel, English Cocker Spaniel, English Springer Spaniel, Brittany Spaniel, American Cocker Spaniel, Clumber Spaniel, Sussex Spaniel, Whippet € 50,18
Muscle type phosphofructokinase deficiency (PFK) is an inherited glycogen storage disease. It is caused by a mutation, which leads to a lack of phosphofructokinase subunits or activity. Without the PFK enzyme muscle cells and erythrocytes are not able to produce enough adequate energy for their needs. Therefore affected dogs display the following intermittent, clinical signs: weakness, lethargy, exercise intolerance, poor performance, muscle cramps, anaemia, jaundice and dark-coloured urine. Dark-coloured urine, a hallmark of this disorder, usually appears after strenuous exercise or after excessive barking, panting or heat exposure and is caused by the destruction of the erythrocytes. More information...
i H872 Pituitary dwarfism German Shepherd, Saarloos Wolfhond, Czechoslovakian Wolfdog, Belgian Shepherd, Dutch Shepherd Dog € 50,18
Dogs, affected by dwarfism, always show a combined deficiency of GH, TSH, LH/FSH and Prolactine. The hormone ACTH is present at normal levels. Cysts may occur in the hypophysis, however as this phenomenon is not always present the absence of cycts may lead to an incorrect diagnosis. A second causative mutation is known (ACA insertion). Compound heterozygosity also leads to dwarfism More information...
i H457 POAG / PLL Primary Glaucoma and Lens Luxation Shar Pei € 50,18
Primary open angle glaucoma (POAG) is a leading cause of blindness in dogs. Elevated intraocular pressure is the most important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown. Primary Lens Luxation (PLL) is a well-recognized, painful and blinding inherited eye condition that affects many breeds of dog, particularly terrier and terrier-type breeds. In affected dogs the fibres which support the lens are broken down or disintegrated. As a result, the lens falls into the wrong position within the eye. This results in a loss of vision. POAG and PLL are inherited as autosomal recessive traits. In Chinese Shar-Pei, a mutation in ADAMTS17 was found to be associated with a diagnosis of POAG, PLL or both. However, it is not yet clear whether these cases are classic PLL or represent a chronic disease process with POAG as the only primary disease. More information...
i H509 Polycystic kidney disease (PKD1) Bull Terrier, Miniature Bull Terrier € 50,18
Polycystic Kidney Disease (PKD) occurs frequently in animals. During the life of an affected dog, cysts appear in the kidneys. These cysts put pressure on the healthy kidney-tissue, which leads to a loss of function of the affected kidneys. Symptoms that occur are loss of hunger, too much consumption of water and a loss of weight. More information...
i H438 Polycythemia All breeds € 50,18
Primary polycythemia is classified as a syndrome with a chronic hematocrit elevation with low circulating erythropoietin (EPO) levels, consequently leading to an abnormal volume of red blood cells in the blood. The frequency of Polycythemia in dogs is unknown and probably underestimated because it is often associated with nonspecific symptoms that can be attributed to various diseases. More information...
i H914 Polyneuropathy 1 Greyhound € 50,18
In 2010, researchers have identified a mutation leading to polyneuropathy of juvenile dogs. Owners of affected dogs report exercise intolerance and walking difficulties in early stages of the disease. In the later stages, the disease is characterized by severe muscle atrophy, ataxia and dysphonia. No behavioral abnormalities, retardation or learning difficulties were observed. Trembling and collapse occurred after exercise. More information...
i H495 Polyneuropathy 2 Alaskan Malamute € 50,18
Researchers have identified a mutation leading to polyneuropathy of juvenile dogs. Owners of affected dogs report exercise intolerance and walking difficulties in early stages of the disease. In the later stages, the disease is characterized by severe muscle atrophy, ataxia and dysphonia. No behavioral abnormalities, retardation or learning difficulties were observed. Trembling and collapse occurred after exercise. More information...
i H379 Polyneuropathy 3 (LPN1) Leonberger, Saint Bernard € 50,18
Heritable polyneuropathies are a heterogenous group of diseases which affect the peripheral nervous system. In the Leonberger and Saint Bernards breeds, the age-of-onset of clinical signs can vary from less than 1 year up to 11 years of age. Dogs with juvenile-onset disorder typically have a more severe and rapidly progressing course of disease. This suggests the existence of at least two distinct polyneuropathies in the breeds. A likely causative mutation for the juvenile onset form of the disease, termed LPN1, was found in the ARHGEF10 gene. This gene is involved in neuronal growth and axonal migration. Dogs homozygous for the mutation typically show onset of clinical signs before four years of age. More information...
i H342 Polyneuropathy 4 (LPN2) Leonberger € 50,18
Heritable polyneuropathies are a heterogenous group of diseases which affect the peripheral nervous system. In the Leonberger breed, the age-of-onset of clinical signs can vary from less than 1 year up to 11 years of age. Dogs with juvenile-onset disorder (LPN1) typically have a more severe and rapidly progressing course of disease. This suggests the existence of at least two distinct polyneuropathies in the breed. A likely causative mutation for a second inherited form of the disease with a wider range of onset, termed LPN2, was found in the GJA9 gene. This gene encodes a protein which is an important component of peripheral myelinated nerve fibers. The inheritance of LPN2 is incompletely dominant. More information...
i H371 PRA Basenji € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H390 PRA 2 Sheltie € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H682 PRA 5 Medium Spitz, Miniature Spitz, Dachshund, Longhair Dachshunds, Wolfspitz, Miniature Longhaired Dachshund, Schnauzer, Pomeranian, Giant Spitz € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H394 PRA BBS4 Hungarian Puli € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H372 PRA crdPRA Wire Haired Dachshund € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H382 PRA erd Norwegian Elkhound € 50,18
Early retinal degeneration (erd) is a canine early onset autosomal recessive disease corresponding to Leber Congenital Amaurosis in humans. It is characterized by aberrant functional and structural development of rod photoreceptor inner and outer segments, and of both rod and cone synapses, with subsequent retinal degeneration. More information...
i H373 PRA type 3 Tibetian Terrier, Tibet Spaniel € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H349 PRA-B Risk Variant Miniature Schnauzer € 111,17
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H704 prcd PRA (partnerlab) American Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Chesapeake Bay Retriever, Chinese Crested, English Cocker Spaniel, Finnish Lapphund, Golden Retriever, Kuvasz, Labradoodle, Labrador Retriever, Lapponian Herder, Miniature and Toy Poodle, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, Spanish Water Dog, Swedish Lapphund, Coton de Tulear, Manchester Terrier, English Springer Spaniel, Entlebucher Mountain Dogs, Lancashire Heeler, Australian Labradoodle, Tibetian Terrier, Goldendoodle, Jack Russell Terrier, Wolfspitz, Miniature American Sheperd, Schipperke, Black Russian Terrier, Karelian Beardog, Lagotto Romagnolo (Romagna Water Dog), Markiesje, Giant Schnauzer, Yorkshire Terrier, Cockapoo, Dwarf Poodle, Australian Silky Terriër, Lab/Golden Cross, Moyen Poodle, Australian Shepherd Miniature & Toy, Norwegian Elkhound, Japanese Chin, Portuguese Podengo Pequeno, Hungarian Puli, Bolognese, Field Spaniel, Norrbottenspitz, Russian-European Laika, Serbian Hound, Xoloitzcuintli, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H700 prcd PRA (patent owner Optigen) American Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Australian Stumpy Tail Cattle Dog, Chesapeake Bay Retriever, Chinese Crested, English Cocker Spaniel, Entlebucher Mountain Dog, Finnish Lapphund, Golden Retriever, Kuvasz, Labradoodle, Labrador Retriever, Lapponian Herder, Miniature and Toy Poodle, Nova Scotia Duck Tolling Retriever, Portuguese Water Dog, Spanish Water Dog, Swedish Lapphund, Coton de Tulear, Manchester Terrier, Lancashire Heeler, Australian Labradoodle, Tibetian Terrier, Goldendoodle, Jack Russell Terrier, Wolfspitz, Miniature American Sheperd, Black Russian Terrier, Karelian Beardog, Lagotto Romagnolo (Romagna Water Dog), Markiesje, Giant Schnauzer, Yorkshire Terrier, Schipperke, Cockapoo, Dwarf Poodle, Australian Silky Terriër, Lab/Golden Cross, Moyen Poodle, Australian Shepherd Miniature & Toy, Norwegian Elkhound, Japanese Chin, Portuguese Podengo Pequeno, Hungarian Puli, Bolognese, Field Spaniel, Norrbottenspitz, Russian-European Laika, Serbian Hound, Xoloitzcuintli, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 130,23
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H439 Prekallikrein deficiency Shih Tzu € 50,18
Prekallikrein (PK) deficiency is an uncommon disorder in dogs. Symptoms include a suspicion of neurological defects and a prolonged activated partial thromboplastin time (aPTT) and normal prothrombin time (PT) with no hemostatic defects. More information...
i H414 Primary Ciliary dyskinesia Sheepdogs, Old English Sheepdog, Tibetian Terrier € 50,18
Primary ciliary dyskinesia (PCD) is an inherited disorder characterized by recurrent infections of the upper and lower respiratory tract, reduced fertility in males and situs inversus in about 50% of affected individuals (Kartagener syndrome). It is caused by motility defects in the respiratory system that are responsible for airway clearance, the parts that propel sperm cells and the nervous system that determine left-right asymmetry. More information...
i H383 Primary Glaucoma Norwegian Elkhound € 50,18
Primary open angle glaucoma is a leading cause of blindness in dogs. Elevated intraocular pressure is the most important risk factor. Increased resistance to outflow of aqueous humor through the trabecular meshwork causes elevated intraocular pressure, but the specific mechanisms are unknown. More information...
i H374 Primary Hyperoxaluria Coton de Tulear, Tibet Spaniel € 50,18
This disease is characterized by tubular necrosis with extensive oxalate crystal deposition. More information...
i H849 Primary Lens Luxation (PLL) Tibetian Terrier, Jack Russell Terrier, Lancashire Heeler, Chinese Crested, Australian Cattle Dog, Rat Terrier, Tenterfield Terrier, Toy Fox Terrier, Volpino Italiano, Miniature Bull Terrier, Parson Russel Terrier, Jagd Terrier, Patterdale Terrier, Sealyham Terrier, Welsh Terrier, Wire-haired Fox Terrier, Yorkshire Terrier, Border Collie € 50,18
Primary Lens Luxation (PLL) is a well-recognised, painful and blinding inherited eye condition that affects many breeds of dog, particularly terrier and terrier-type breeds. In affected dogs the fibres which support the lens are broken down or disintegrated. As a result, the lens falls into the wrong position within the eye. This results in a loss of vision. More information...
i H740 Pyruvate Dehydrogenase Phosphatase 1 (PDP1) Clumber Spaniel, Sussex Spaniel € 50,18
Exercise intolerance syndromes are well known to be associated with inborn errors of metabolism affecting glycolysis and fatty acid oxidation. A canine model was used to identify a deficit in PDP1, the phosphatase enzyme that activates the pyruvate dehydrogenase complex. Homozygosity produces severe exercise intolerance. Skeletal muscle myopathy is a hereditary muscle disorder in which there is a deficiency of muscle fibers leading to a notable decrease in skeletal muscle mass. More information...
i H741 Pyruvate kinase Deficiency (PKDef) Labrador Retriever € 50,18
Pyruvate kinase (PK) is an enzyme critical to the anaerobic glycolytic pathway of energy production in the erythrocyte. If red blood cells are deficient in PK they are unable to sustain normal cell metabolism and hence are destroyed prematurely. This deficiency manifests as an hemolytic anemia of variable severity with a strong regenerative response. Also associated with the disease in dogs but not cats is a progressive myelofibrosis and osteosclerosis of unknown etiology and this feature, along with liver failure, is the major cause of death in affected dogs. More information...
i H454 Pyruvatekinase Deficiency (PKDef) 2 Pug Dog € 50,18
Pyruvate kinase (PK) is an enzyme critical to the anaerobic glycolytic pathway of energy production in the erythrocyte. If red blood cells are deficient in PK they are unable to sustain normal cell metabolism and hence are destroyed prematurely. This deficiency manifests as an hemolytic anemia of variable severity with a strong regenerative response. Also associated with the disease in dogs but not cats is a progressive myelofibrosis and osteosclerosis of unknown etiology and this feature, along with liver failure, is the major cause of death in affected dogs. More information...
i H455 Pyruvatekinase Deficiency (PKDef) 3 Beagle € 50,18
Pyruvate kinase (PK) is an enzyme critical to the anaerobic glycolytic pathway of energy production in the erythrocyte. If red blood cells are deficient in PK they are unable to sustain normal cell metabolism and hence are destroyed prematurely. This deficiency manifests as an hemolytic anemia of variable severity with a strong regenerative response. Also associated with the disease in dogs but not cats is a progressive myelofibrosis and osteosclerosis of unknown etiology and this feature, along with liver failure, is the major cause of death in affected dogs. More information...
i H768 rcd1 PRA Irish setter € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H769 rcd1a PRA Sloughi € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H801 rcd2 PRA Smooth Collies, Rough Collies, Bearded Collie, Border Collie € 130,23
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H770 rcd3 PRA Cardigen Welsh Corgi, Chinese Crested € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H511 rcd4 PRA Gordon Setter, Irish setter, Polish Lowland Sheepdog (Polski Owczarek Nizinny - PON), Miniature and Toy Poodle, Poodle, Australian Cattle Dog, Tibetian Terrier € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H794 Retinal Dysplasia Retinal Folds RD OSD 1 Labrador Retriever € 50,18
Retinal Dysplasia (retinal folds, RD) is a common clinical observation in many dog breeds. Since many retinal folds are benign and of unknown heritability, veterinary ophthalmologists will often advise that breeding dogs with RD is an acceptable option. However in a few breeds RD is accompanied with a serious inherited syndrome called OSD (OculoSkeletal Dysplasia). OSD is a severe condition in which the dogs show a variety of skeletal malformations, including shortened limbs (dwarfism), and blindness at an early age; the blindness results from a generalized malformation of the retina. More information...
i H426 Retinal Dysplasia Retinal Folds RD OSD 2 Samoyed € 130,23
Retinal Dysplasia (retinal folds, RD) is a common clinical observation in many dog breeds. Since many retinal folds are benign and of unknown heritability, veterinary ophthalmologists will often advise that breeding dogs with RD is an acceptable option. However in a few breeds RD is accompanied with a serious inherited syndrome called OSD (OculoSkeletal Dysplasia). OSD is a severe condition in which the dogs show a variety of skeletal malformations, including shortened limbs (dwarfism), and blindness at an early age; the blindness results from a generalized malformation of the retina. More information...
i H423 SCID Jack Russell Terrier € 50,18
Animals affected by SCID have severe loss of the immune systems. Young puppies die of various infections soon after birth. More information...
i H456 SCID 2 Frisian Water Dogs € 50,18
The inherited disease Severe Combined Immune Deficiency (SCID) is characterised by profound defects in cellular and humoral immunity and is inevitably fatal by 4 months of age. Due to an almost complete absence of the immune system, young animals die due to a variety of infections. More information...
i H388 Sensory Neuropathy Border Collie € 50,18
Sensory neuropathy is an inherited disease, which affects the Border Collie breed. Axonal degeneration and large nerve fibre loss mainly involves sensory nerves while mixed motor and sensory nerves are impaired to a lesser extent. As a consequence, progressive ataxia, intermittent knuckling of the paws and self-mutilation occurs. A large inversion, disrupting the FAM134B gene was identified as the cause of the disease. More information...
i H336 Sensory Neuropathy 3 AMS German Pointers, English Springer Spaniel, Pointer, German Shorthaired Pointer, English Cocker Spaniel, French Spaniel € 50,18
A heritable, recessive sensory neuropathy was described in the German short-haired Pointer, English Pointer, English Springer Spaniel and French Spaniel breeds. The main characteristic of the disease is insensitivity to pain in the paws which can be accompanied with self-mutilation. It’s also known as Acral mutilation syndrome (AMS). A genetic study identified the likely causal mutation in a long non-coding RNA, GDNF-AS. The mutation disrupts a regulatory region leading to an impaired development of sensory neurons. More information...
i H510 Skeletal Dysplasia 2 (SD2) Labrador Retriever, American Cocker Spaniel, Cavalier King Charles Spaniel, Sussex Spaniel € 50,18
The appearance of a dog with skeletal dysplasia is characterized by short legs with normal body length and width. In most cases the forelegs are slightly more affected than the hind legs. More information...
i H303 Spinocerebellar ataxia Jack Russell Terrier, Parson Russel Terrier, Tenterfield Terrier, Toy Fox Terrier, Smooth haired fox terrier € 50,18
Usually, heritable ataxia in dogs is presented with a wide range of clinical symptoms, histopathologic findings and variable age of onset. The observed heterogeneity led to the assumption of different heritable forms of ataxia segregating in dogs. A mutation in KCNJ10 was identified as the cause of an autosomal recessive form called 'spinocerebellar ataxia with myokymia, seizures or both'. More information...
i H683 Spinocerebellar Ataxia 2 Alpine Dachsbracke € 50,18
Usually, heritable ataxia in dogs is presented with a wide range of clinical symptoms, histopathologic findings and variable age of onset. The observed heterogeneity led to the assumption of different heritable forms of ataxia segregating in dogs. In Parson Russell Terriers a late onset form of spinocerebellar ataxia could be traced back to a mutation in the CAPN1 gene and additional genetic causes cannot be ruled out in this breed. Another breed specific missense variant, most likely responsible for an early-onset form of spinocerebellar ataxia was identified in Alpine Dachsbracke dogs. More information...
i H328 Spinocerebellar ataxia, LOA (Late Onset Ataxia) Jack Russell Terrier, Parson Russel Terrier € 50,18
Usually, heritable ataxia in dogs is presented with a wide range of clinical symptoms, histopathologic findings and variable age of onset. The observed heterogeneity led to the assumption of different heritable forms of ataxia segregating in dogs. In Parson Russell Terrier dogs the spinocerebellar ataxia (SCA) has a later onset than other known heritable ataxias and therefore, a different genetic cause is likely. A strongly associated mutation was identified in the CAPN1 gene. However, not all affected dogs were homozygous for the mutation in the study, and different genetic causes cannot be ruled out for the disease. More information...
i H440 Thrombasthenia Otterhound € 50,18
An inherited intrinsic functional disorder of platelets has also been identified as Glanzmann’s thrombasthenia (GT). The disease is characterized by failure of platelets to aggregate. Clinical signs consist primarily of mucosal bleeding. Bleeding episodes may be mild to severe. More information...
i H447 Thrombasthenia 2 Great Pyrenees € 50,18
An inherited intrinsic functional disorder of platelets has also been identified as Glanzmann’s thrombasthenia (GT). The disease is characterized by failure of platelets to aggregate. Clinical signs consist primarily of mucosal bleeding. Bleeding episodes may be mild to severe. More information...
i H441 Thrombocytopaenia Cavalier King Charles Spaniel, Labrador Retriever € 50,18
The mutation causes an abnormal protein which reduces the forming of blood platelets but they are larger (mega- or macrothrombocytes), functional is the number of offset by the size. CKCS affected animals have no problem with their blood clotting, the clinical relevance is limited by giving an explanation for the presence of macrothrombocytes during routine heamatological examination in some individuals of this breed. Macrothrombocytes, however, can also be the result of a pathological process, without this genetic explanation,in this case it should be followed up. More information...
i H442 Thrombopathia Basset € 50,18
Affected dogs experienced epistaxis, gingival bleeding, and petechiation. Platelet aggregation and release responses to all agonists, except thrombin, are markedly impaired. Clinical signs consist primarily of mucosal bleeding. Bleeding episodes may be mild to severe. More information...
i H448 Thrombopathia 2 American Eskimo Dog € 50,18
Affected dogs experienced epistaxis, gingival bleeding, and petechiation. Platelet aggregation and release responses to all agonists, except thrombin, are markedly impaired. Clinical signs consist primarily of mucosal bleeding. Bleeding episodes may be mild to severe. More information...
i H449 Thrombopathia 3 Landseer € 50,18
Affected dogs experienced epistaxis, gingival bleeding, and petechiation. Platelet aggregation and release responses to all agonists, except thrombin, are markedly impaired. Clinical signs consist primarily of mucosal bleeding. Bleeding episodes may be mild to severe. More information...
i H787 Trapped Neutrophil Syndrome (TNS) Border Collie, Bearded Collie, Rough Collies, Smooth Collies € 50,18
Trapped Neutrophil Syndrome (TNS) is an inherited fatal immune disorder. Neutrophils are the precursors to white blood cells, produced in the bone marrow and, in a normal animal, released into the blood to fight infections. In a TNS affected animal these neutrophils cannot be released from the bone marrow so the animal is unable to mount an effective immune response to infection. Symptoms can vary greatly, depending on which infections the pup happens to contract. A bone marrow biopsy is the best way to detect the disease, if the neutrophil levels in the bone marrow are higher than those in the blood it is an indication that these are trapped hence trapped neutrophil syndrome. More information...
i H432 Tremor, X-linked English Springer Spaniel € 50,18
The differentiation of the oligodendrocytes culminate in the production of the myelin-specific proteins and the elaboration of membrane processes that ensheath the axon. Mutations in the major proteins building myelin, are characterized by a significant reduction in the number of mature oligodendrocytes, resulting in severe hypomyelination, tremor and early death (shaking pups). More information...
i H771 Type A PRA Miniature Schnauzer € 130,23
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H433 Vitamin D-deficiency rickets, type II Wolfspitz, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 50,18
Hypocalcemic rickets encompasses a group of disorders in which intestinal absorption of calcium is insufficient to meet the calcium demands of a growing skeleton. Causes include dietary calcium deficiency and insufficient intestinal absorption of calcium caused by vitamin D deficiency or decreased vitamin D activity. As a result, bones lack their strength and are softened. More information...
i H642 Von Willebrand disease 3 - 2 Dutch Kooikerhondje € 50,18
Von Willebrand disease (vWD) is the most common inherited bleeding disorder, which is highly heterogeneous ranging from an asymptomatic laboratory abnormality to a life threatening bleeding. The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF). It has been classified into six subgroups based on evaluation of the vWF level and function. The disease is characterized by the abnormally low production of von Willebrands factor which plays a key role in the complex process of clotting a damaged blood vessel. More information...
i H677 Von-Willebrands Disease Type 1 Bernese Mountain Dog, Coton de Tulear, Doberman Pinscher, Drentsche Patrijshond, German Pinscher, Kerru Blue Terrier, Manchester Terrier, Papillion, Pembroke Welsh Corgi, Poodle, Stabijhoun, Dobermann, Australian Shepherd, Australian Silky Terriër, Cairn Terrier, Wolfspitz, Great Dane, Pug Dog, Schipperke, Volpino Italiano, Hungarian Puli, Medium Spitz, Miniature Spitz, Pomeranian, Giant Spitz, Phalene € 50,18
Von Willebrand disease (vWD) is the most common inherited bleeding disorder, which is highly heterogeneous ranging from an asymptomatic laboratory abnormality to a life threatening bleeding. The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF). It has been classified into six subgroups based on evaluation of the vWF level and function. The disease is characterized by the abnormally low production of von Willebrands factor which plays a key role in the complex process of clotting a damaged blood vessel. Because it is very uncommon for carriers to show symptoms of vWD this condition is considered to be recessive. More information...
i H743 Von-Willebrands Disease Type 2 German Pointers, American Cocker Spaniel, Australian Stumpy Tail Cattle Dog, Chihuahua, Wolfspitz, Miniature and Toy Poodle, Poodle, Canaan Dog, Spinone Italiano, Xoloitzcuintli, Giant Spitz, Medium Spitz, Miniature Spitz, Pomeranian € 50,18
Von Willebrand disease (vWD) is the most common inherited bleeding disorder, which is highly heterogeneous ranging from an asymptomatic laboratory abnormality to a life threatening bleeding. The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF). It has been classified into six subgroups based on evaluation of the vWF level and function. The disease is characterized by the abnormally low production of von Willebrands factor which plays a key role in the complex process of clotting a damaged blood vessel. More information...
i H345 Von-Willebrands Disease Type 2-2 German Wirehaired Pointer, German Shorthaired Pointer € 50,18
Von Willebrand disease (vWD) is the most common inherited bleeding disorder, which is highly heterogeneous ranging from an asymptomatic laboratory abnormality to a life threatening bleeding. The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF). It has been classified into six subgroups based on evaluation of the vWF level and function. The disease is characterized by the abnormally low production of von Willebrands factor which plays a key role in the complex process of clotting a damaged blood vessel. More information...
i H744 Von-Willebrands Disease Type 3 Scottish Terrier, Sheltie € 50,18
Von Willebrand disease (vWD) is the most common inherited bleeding disorder, which is highly heterogeneous ranging from an asymptomatic laboratory abnormality to a life threatening bleeding. The condition is caused by a quantitative or qualitative deficiency of von Willebrand factor (vWF). It has been classified into six subgroups based on evaluation of the vWF level and function. The disease is characterized by the abnormally low production of von Willebrands factor which plays a key role in the complex process of clotting a damaged blood vessel. More information...
i H696 Warburg Micro Syndrome 1 (WARBM1) € 50,18
Warburg micro syndrome (WARBM) in human is a genetic heterogeneous disease characterized by microcephaly, intellectual disability, brain, ocular, and endocrine anomalies. In Huskies, microphtalmia and progressive neurological disorders (i.e. ataxia) have been observed. More information...
i H772 X Linked PRA1 (XL PRA1) Samoyed € 50,18
Progressive Retinal Atrophy (PRA) refers to a group of inherited blinding canine diseases. Depending on the mutation the blindness develops faster or slower. A large number of varieties of PRA are currently known to affect several breeds. (Scientific) research is continuously developing new tests. More information...
i H745 X-SCID Welsh Corgi € 50,18
The X-linked inherited disease Severe Combined Immune Deficiency (SCID) is characterised by profound defects in cellular and humoral immunity and is inevitably fatal by 4 months of age. Due to an almost complete absence of the immune system, young animals die due to a variety of infections. More information...
Test on demand Breed Price (incl. VAT) Order
i H340 Canine Brachycephaly Boston Terrier, Boxer, Bull Mastif, Cane Corso, Cavalier King Charles Spaniel, Chihuahua, French Bulldog, Japanese Chin, Rottweiler, Shih Tzu, Pug Dog, Affenpinscher, Griffon Bruxellois, English Bulldog, Mastiffs, Neapolitan Mastiff, Pekingese, Dogue de Bordeaux On request
Facial retrusion is common to brachycephalic dog breeds. A genetic study identified a quantitative trait loci (QTL) on CFA1, which considerably contributes to face length variation. Most likely causative is an intronic LINE-1 sequence within the SMOC2 gene, which reduces SMOC2 expression in brachycephalic dogs. The LINE-1 sequence was found in 91,5% of chromosomes of brachycephalic dogs but only 2,1% of chromosomes of non-brachycephalic dogs. More information...
i H341 Cerebellar Ataxia (SDCA2) Belgian Shepherd On request
Usually, heritable ataxia in dogs presents with a wide range of clinical symptoms, histopathologic findings and variable age of onset. The observed heterogeneity led to the assumption of different heritable forms of ataxia segregating in dogs. A form called “spongy degeneration with cerebellar ataxia, subtype 1” (SDCA1) is caused by a mutation in the KCNJ10 gene. The variant was exclusively found in Malinois dogs, a variety of the Belgian Shepherd breed and showed an autosomal recessive form of inheritance. However, not all affected Belgian Shepherd dogs were homozygous for that variant. A second study revealed a SINE insertion in the ATP1B2 gene as the cause of “spongy degeneration with cerebellar ataxia, subtype 2” (SDCA2). Hence, as both mutations don’t explain all cases of affected Belgian Shepherd dogs, more than two forms of heritable ataxias must exist in the breed. More information...
i H376 Dog_Skull Diversity All breeds On request
The mutation which is tested has an effect on the size of the head More information...
i H464 Gastric Dilatation-Volvulus_1 Great Dane On request
Gastric dilatation-volvulus (GDV) especially occurs in large breeds of dogs. Dilatation of the stomach is caused by accumulation of gas, which results from bacterial fermentation and torsion of the stomach on its axis prevents the escape of gas. The expansion of the stomach leads to the compression of vital blood vessels and thus to a life-threatening situation. The causes of GDV are not clearly understood, but genetic factors seem to be important risk factors. Possibly variations in genes of the immune system may predispose dogs to GDV. This hypothesis was followed up in a study and associations between specific alleles of the genes DLA88, DRB1 and TLR5 and GDV were discovered. More information...
i H465 Gastric Dilatation-Volvulus_2 Great Dane On request
Gastric dilatation-volvulus (GDV) especially occurs in large breeds of dogs. Dilatation of the stomach is caused by accumulation of gas, which results from bacterial fermentation and torsion of the stomach on its axis prevents the escape of gas. The expansion of the stomach leads to the compression of vital blood vessels and thus to a life-threatening situation. The causes of GDV are not clearly understood, but genetic factors seem to be important risk factors. Possibly variations in genes of the immune system may predispose dogs to GDV. This hypothesis was followed up in a study and associations between specific alleles of the genes DLA88, DRB1 and TLR5 and GDV were discovered. More information...
i H466 Gastric Dilatation-Volvulus_3 Great Dane On request
Gastric dilatation-volvulus (GDV) especially occurs in large breeds of dogs. Dilatation of the stomach is caused by accumulation of gas, which results from bacterial fermentation and torsion of the stomach on its axis prevents the escape of gas. The expansion of the stomach leads to the compression of vital blood vessels and thus to a life-threatening situation. The causes of GDV are not clearly understood, but genetic factors seem to be important risk factors. Possibly variations in genes of the immune system may predispose dogs to GDV. This hypothesis was followed up in a study and associations between specific alleles of the genes DLA88, DRB1 and TLR5 and GDV were discovered. More information...
i H813 Glycogen Storage Disease GSD Type IIIa (GSDIIIa) Curly-Coated Retriever On request
Glycogen storage disease type IIIa (GSD IIIA) is an inherited abnormality of glucose metabolism. Normally, excess glucose is stored in many tissues as glycogen. If energy is needed, glucose molecules are removed from glycogen. The ability to add and remove glucose molecules from glycogen efficiently is dependent on its highly branched structure. A mutation has been identified in the AGL-gene, which was linked to the disease. Deficiency of AGL activity leads to abnormal glycogen accumulation in myocytes, hepatocytes, and neurones, causing variably progressive, benign to lethal organ dysfunctions. More information...
i H417 Leukoencephalomyelopathy Sheepdogs, Australian Cattle Dog On request
Spongiform leukoencephalomyelopathy shows widespread vacuolation of white matter of the brain and spinal cord. Affected dogs developed tremors at 2 –9 weeks of age followed by progressive neurological worsening nerve dysfunction. More information...
i H723 MDR1 (patent owner) All breeds On request
The Multidrug Resistance gene 1 (the MDR1 gene) plays an important role in the barrier between blood capillaries and brain tissue. Dogs suffering from oversensitivity for Ivermectine have been documented to be susceptible to neurotoxicity induced by many other drugs as well. More information...
i H350 Ridge disposition (Dermoid sinus) Rhodesian Ridgeback, Thai Ridgeback Dog On request
The breed-defining dorsal ridge in Rhodesian Ridgeback dogs is the result of a ~ 133,000 base pair duplication on chromosome 18 (Ridge allele). This duplication is absent in dogs without a ridge. The ridge trait is inherited in a dominant fashion, a single copy of this duplication results in appearance of a ridge. Dogs with two copies of the duplication are indistinguishable from dogs with one copy of the Ridge allele, but are at substantially greater risk for the development of dermoid sinus, a neural tube defect that is caused by incomplete separation of tissue layers during development. Affected dogs develop an inappropriate connection between the dermal surface and the spinal cord. This growth can become infected and lead to the development of abscesses and sepsis. In many cases, dermoid sinus can be fatal. More information...
i H684 Subvalvular Aortic Stenosis New Foundlander On request
Subvalvular aortic stenosis (SAS) is one of the most commonly reported congenital heart defects in dogs. It is characterized by an abnormal ridge or ring of tissue in the left ventricular outflow tract (LVOT) that hinders ventricular ejection, generates pressure overload, and increases velocity of blood flow into the aorta. SAS is known to be an inherited defect in Newfoundland dogs. A genetic study identified a mutation in the PICALM gene, which was associated with the development of SAS in this breed. However, the relevance of this mutation is highly controversial, because a replication study failed to show any association between the PICALM variant and SAS and therefore classified the mutation as a neutral variant that occurs at high frequencies in Newfoundland dogs and is rare or absent in most other dog breeds. More information...
i H309 Weight and Appetite in Obesity-Prone dogs Labrador Retriever, Flat-Coated Retriever On request
As in humans, also in dogs obesity is associated with a variety of health problems and reduced lifespan. A considerable and increasing number of dogs is obese. However, susceptibility to obesity varies between dog breeds due to the genetic background. Labrador retrievers have the greatest documented obesity prevalence. A genetic study performed with animals of this breed and the closely related flat-coat retrievers identified a mutation, which is associated with increased body weight, adiposity and food motivation in these breeds. More information...
i H471 X-linked hypohidrotic ectodermal dysplasia Short-Haired Dachshund On request
X-linked ectodermal dysplasia (XLHED) belongs to the ectodermal dysplasias (ED), which are a group of genetically heterogenous diseases. This skin condition is characterized by absent or abnormal teeth, hypotrichosis, absent sweat glands and symmetrical hairlessness. Affected animals are more susceptible to pulmonary infectious disease than normal dogs. Chronic nasal and ocular discharges are common. In a family of shorthaired standard Dachshunds, a very recent de-novo 1-basepair deletion in the ectodysplasin-A (EDA) gene was identified as cause of the disease. More information...
Other genetic traits Breed Price (incl. VAT) Order
i H820 Coat Colour A-locus All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Agouti gene (ASIP gene) is responsible for the production of a protein that regulates the distribution of black pigment (eumelanin) within the hair shaft. This gene is also known as the A-locus and determines whether an animal expresses an agouti appearance, and if so what type, by controlling the distribution of pigment in individual hairs. The agouti pattern can be seen in both black-based and red-based colours. The coat colour is further complicated by the interaction with the K-locus and the E-locus. The agouti pattern is only expressed if on the K-locus no copy of the KB allele is present in combination with at least one copy of the E or Em allele on the E-locus. The Coat Colour A-Locus test (H820) tests for the genetic status of the A-locus. The A-locus has four variants (alleles). The most dominant allele is Ay, followed by aw, then at, then a. The dominant Ay allele produces a sable or fawn coat colour. The allele aw produces a colour known as wild sable or wild type. With this colouration, the hairs switch pigmentation from black to reddish or fawn. This colour is sometimes seen in German Shepherds and other shepherd breeds. The allele at results in tan points (tan markings on a dark dog) and produces black-and-tan and tricolour dogs. A tricolour dog is black-and-tan plus white. The allele a is also called the recessive black allele and results in a solid black/brown/blue/lilac or bicolour dog. Some breeds are fixed for only one variant. The Norwegian Elkhound is fixed for the aw allele and the Beagle is fixed for the at allele. In many breeds 2 or 3 alleles are present.
More information...
i H733 Coat Colour B-locus All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Tyrosinase-Related Protein 1 (TYRP1) gene, also known as Brown gene or B-Locus controls the dilution from black pigment to brown. The TYRP1 gene has no effect on the hair colour of dogs that are homozygous ee for the E-Locus as they do not have black pigment, but does have an effect on the colour of the nose and foot pads of these dogs. The Coat Colour B-Locus (H733) tests for the genetic status of the B-Locus. The B-Locus has four variants (alleles). The B allele is dominant and does not dilute the black pigment. From the recessive b allele three variants exist bs, bd and bc. All three variants of the recessive b allele have the same effect resulting in dilution of the black pigment into brown/chocolate/liver. Only when the dog has two copies of the recessive allele b (homozygous bb) the black pigment will be diluted to brown/chocolate/liver. For dogs that are red/yellow/cream and carry two copies of the recessive allele b the hair colour is not diluted but the colour of the nose and foot pads is changed from black to brown. In some breeds other mutations are present that cause chocolate colour that have not been identified yet. For example, the mutation for chocolate in French Bulldogs has not been found yet and the genetic basis is not known at this time
More information...
i H461 Coat Colour D-Locus (MLPH) 2 Chow Chow, Sloughi, Thai Ridgeback Dog € 50,18
"During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests. The dilute gene (MLPH gene) is responsible for the intensity of the coat colour by affecting the distribution of melanin-containing cells. This gene is also known as the D-Locus and dilutes all colours. Besides the hair colour also the colour of the nose is diluted and the colour of the eyes lightens to amber. In some breeds however, the coat colour could not be explained by a previously detected MLPH mutation. Hence, a second MLPH variant must exist, which in fact could be identified in a study carried out in Chow Chows. The variant was denoted d2 in order to differentiate it from the formerly detected variant d, now called d1. The dilute dogs were all either compound heterozygous d1/d2 or homozygous d2/d2, whereas the non-dilute dogs carried at least one wildtype allele D. Besides Chow Chows, the d2 variant was found in Sloughis and Thai Ridgebacks. " More information...
i H847 Coat Colour D-Locus Improved (MLPH) All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The dilute gene (MLPH gene) is responsible for the intensity of the coat colour by affecting the distribution of melanin-containing cells. This gene is also known as the D-Locus and dilutes all colours. Besides the hair colour also the colour of the nose is diluted and the colour of the eyes lightens to amber. The Coat Colour D-Locus Improved (MLPH) test (H847) tests for the genetic status of the D-Locus. The D-Locus has two variants (alleles). The allele D is dominant and does not have an effect on the coat colour. Only when the dog has two copies of the recessive allele d the coat colour is diluted. The dilution of black results in grey, also called blue or charcoal. The coat ranges from silver to almost black, but all have a blue nose. Chocolate/brown/liver dilutes into lilac/light tan/Isabella, their noses vary from pink, liver to isabella. Red/yellow/cream dilutes into champagne. In some breeds another, yet unidentified, mutation is present that causes coat colour dilution. This unidentified mutation is known to occur in Doberman Pinscher, French Bulldog, Italian Greyhound, Chow Chow and Shar-Pei.
More information...
i H734 Coat Colour E-locus All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

In each dog two pigments are the basis for their coat colour: black pigment (eumelanin) and red/yellow/cream pigment (pheomelanin). The production of black and red/yellow/cream pigment is controlled by the Melanocortin 1 Receptor (MC1R) gene, also known as Extension gene or E-Locus. The Coat Colour E-Locus (H734) and Coat Colour Em-Locus (H818) combined reveal the genetic status of the E-Locus.

The E-Locus has three variants (alleles). The Em allele is dominant over the alleles E and e; allele E is dominant over allele e. The dominant allele Em causes a melanistic face mask. Dogs that are solid black may have the allele Em but the mask is not visible as it is indistinguishable from the body colour. Dogs with white muzzles may have the allele Em but the mask is overridden by white spotting patterns. The Melanistic face mask is present in a variety of breeds (e.g. Afghans, Akitas, Boxers, French Bulldogs, German Shepherds, Great Danes, Greyhounds, Pug Dogs and Whippets). Pug Dogs and Boxers are fixed for the Em allele. The allele E results in a black coat colour and the allele e results in a red coat colour. In Afghan and Saluki hounds a fourth allele has been identified which only is expressed when the dominant black (K-Locus) is not present and the A-Locus is at/at. This fourth allele Eg causes a pattern that is called grizzle or domino. VHLGenetics does not offer a test that detects the Eg allele.
More information...
i H632 Coat Colour E-Locus 2 Australian Cattle Dog € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests. In each dog two pigments are the basis for their coat colour: black pigment (eumelanin) and red/yellow/cream pigment (pheomelanin). The production of black and red/yellow/cream pigment is controlled by the Melanocortin 1 Receptor (MC1R) gene, also known as Extension gene or E-Locus. The recessive e-variant is widespread in yellow and red-coloured dogs. By investigating cream-coloured Australian Cattle Dogs whose coat colour could not be explained by the e-variant, an additional variant, termed e2 was detected. More information...
i H818 Coat Colour Em-locus All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

In each dog two pigments are the basis for their coat colour: black pigment (eumelanin) and red/yellow/cream pigment (pheomelanin). The production of black and red/yellow/cream pigment is controlled by the Melanocortin 1 Receptor (MC1R) gene, also known as Extension gene or E-Locus. The Coat Colour E-Locus (H734) and Coat Colour Em-Locus (H818) combined reveal the genetic status of the E-Locus.

The E-Locus has three variants (alleles). The Em allele is dominant over the alleles E and e; allele E is dominant over allele e. The dominant allele Em causes a melanistic face mask. Dogs that are solid black may have the allele Em but the mask is not visible as it is indistinguishable from the body colour. Dogs with white muzzles may have the allele Em but the mask is overridden by white spotting patterns. The Melanistic face mask is present in a variety of breeds (e.g. Afghans, Akitas, Boxers, French Bulldogs, German Shepherds, Great Danes, Greyhounds, Pug Dogs and Whippets). Pug Dogs and Boxers are fixed for the Em allele. The allele E results in a black coat colour and the allele e results in a red coat colour. In Afghan and Saluki hounds a fourth allele has been identified which only is expressed when the dominant black (K-Locus) is not present and the A-Locus is at/at. This fourth allele Eg causes a pattern that is called grizzle or domino. VHLGenetics does not offer a test that detects the Eg allele.
More information...
i H316 Coat Colour H-locus (Harlequin) Great Dane € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The 20S proteasome ß2 subunit (PSMB7) gene is responsible for the Harlequin coat pattern in Great Danes. This gene is also known as H-Locus. Harlequin is a pattern resulting from interaction of the Merle (M-locus) gene and the Harlequin (H-locus) gene on black pigment. The Harlequin gene can modify the Merle gene. The Harlequin pattern is only expressed if on the M-locus at least one copy of the M allele is present in combination with at least one copy of the E or Em allele on the E-locus. Dogs that are not merle, or only have red pigment, cannot express the Harlequin gene. The dominant Merle gene, by itself produces dark spots on a diluted background. If a Merle dog also inherits one copy of the Harlequin gene, the dark spots increase in size and the background pigment is removed (turns white). The Harlequin mutation in Great Danes is in homozygous state (two copies of the mutation) considered embryonic lethal as no live dogs with two copies of the mutation have been observed. This means that pups that are homozygous for the Harlequin mutation do not develop in the uterus and are reabsorbed very early in the development process. Therefore all Harlequin patterned dogs have only 1 copy of the Harlequin mutation. The Coat colour H-locus (Harlequin) test (H316) tests for the genetic status of the H-locus. This gene has two variants (alleles), H and N. The allele H is dominant. One copy of the H allele, together with at least one copy of both the M allele for the M-locus and the E allele for the E-locus results in dogs with the Harlequin pattern. Two copies of the H allele result in early embryonic death. The allele N does have no effect on the coat colour.
More information...
i H819 Coat Colour K-locus All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Beta-defensin gene (CBD103 gene) produces dominant black vs. brindle vs. fawn coat colours. This gene is also known as the K-locus or Dominant black gene. The coat colour is further complicated by the interaction with the E-locus and the A-locus (agouti). The Coat Colour K-Locus (H819) tests for the genetic status of the K-Locus. The K-locus has three variants (alleles). The allele KB is dominant over the alleles kbr and ky; allele kbr is dominant over allele ky. The dominant allele KB, also called dominant black allele, does not allow the agouti gene to be expressed. A dog with at least one copy of the KB allele expresses a base colour, which is determined by the B- and E-Locus. The allele kbr results in brindling and allows the agouti to be expressed but causes brindling of the agouti patterns. The A-Locus (agouti) represents several different colours, such as fawn/sable, wild sable, tan points and recessive black. The allele ky allows the agouti to be expressed without brindling. When a dog has two copies of the ky allele (homozygous ky/ky) the agouti locus determines the dog’s coat colour. The test does not discriminate between the alleles kbr and ky.
More information...
i H630 Coat Colour Merle (partner lab) All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Silver gene (SILV gene), also called premelanosome protein (PMEL17 gene) is responsible for Merle. This gene is also known as M-Locus. Merle only dilutes eumelanin (black) pigment; dogs with two copies of the allele e (homozygous e/e) at E-Locus have no black pigment, thus do not express merle. Merle is an incompletely dominant coat color pattern characterized by irregularly shaped patches of diluted pigment and solid color. Blue and partially blue eyes are typically seen with merle, and merle dogs often have a wide range of auditory and ophthalmologic defects. Breeds with merle coat pattern are Shetland Sheepdog, Collie, Border Collie, Australian Shepherd, Cardigan Welsh Corgi, Catahoula Leopard Dog, Dachshund, Great Dane, Bergamasco Sheepdog and Pyrenean Shepherd. The Coat Colour Merle test (H630) tests for the genetic status of the M-locus. The M-locus has three variants (alleles): M (merle, SINE with longer poly-A tail), Mc (cryptic merle, SINE with shorter poly-A tail) and N (non-merle, no SINE insertion. Dogs with cryptic merle (also called phantom or ghost merle), typically display little to no merling and some may be misclassified as non-merles.
More information...
i H930 Coat Colour Merle (patent owner) All breeds € 95,29
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Silver gene (SILV gene), also called premelanosome protein (PMEL17 gene) is responsible for Merle. This gene is also known as M-Locus. Merle only dilutes eumelanin (black) pigment; dogs with two copies of the allele e (homozygous e/e) at E-Locus have no black pigment, thus do not express merle. Merle is an incompletely dominant coat color pattern characterized by irregularly shaped patches of diluted pigment and solid color. Blue and partially blue eyes are typically seen with merle, and merle dogs often have a wide range of auditory and ophthalmologic defects. Breeds with merle coat pattern are Shetland Sheepdog, Collie, Border Collie, Australian Shepherd, Cardigan Welsh Corgi, Catahoula Leopard Dog, Dachshund, Great Dane, Bergamasco Sheepdog and Pyrenean Shepherd. The Coat Colour Merle test (H930) tests for the genetic status of the M-locus. The M-locus has three variants (alleles): M (merle, SINE with longer poly-A tail), Mc (cryptic merle, SINE with shorter poly-A tail) and N (non-merle, no SINE insertion. Dogs with cryptic merle (also called phantom or ghost merle), typically display little to no merling and some may be misclassified as non-merles.
More information...
i H354 Coat Colour Panda White Spotting German Shepherd, Belgian Shepherd, Dutch Shepherd Dog € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

A mutation in the KIT-gene is associated with a white spotting pattern in German Shepherd Dogs, this pattern is also called Panda White Spotting. The mutation is very recent, it appeared spontaneously in a female born in 2000. The gene for white-spotting is known as the S-locus (MITF-Gene), however this mutation in the German Shepherd dogs is in a different gene then the mutation causing white spotting in other dog breeds. The mutation causes white markings on the face, limbs, belly, neck, and tip of the tail, with the white being concentrated toward the front of the dog, similar to the irish spotting pattern. The amount of white can vary from dog to dog. The mutation that causes the Panda White pattern in German Shepherd dogs is in homozygous state (two copies of the mutation) considered embryonic lethal as no live dogs with the pattern and with two copies of the mutation have been observed. This means that pups that are homozygous for the Panda mutation do not develop in the uterus and are reabsorbed very early in the development process. Dogs that are heterozygous (one copy of the mutation) do not have any health defects associated with the Panda pattern. The Coat Colour Panda White Spotting test (H354) tests for the genetic status of the KIT-gene. This gene has two variants (alleles), P and N. The allele P is dominant. One copy of the P allele results in dogs with the Panda white pattern. Two copies of the P allele result in early embryonic death. The allele N does have no effect on the coat colour.
More information...
i H326 Coat Colour Piebald All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The white spotting patterns that occur in many dog breeds do not have a uniform genetic basis. The Microphthalmia Associated Transcription Factor gene (MITF gene) is associated with many white spotting patterns. This gene is also known as the S-Locus. There are three major white spotting patterns described. One pattern is called “Irish spotting” and is a symmetrical pattern with white markings on the undersides, collar and muzzle, and/or blaze as demonstrated by breeds such as the Boston Terrier, Corgi, Bernese Mountain dog and Basenji. Another pattern of less symmetrical white spotting in which random white spots occur on the body of the dog is often called piebald, parti or random white and is observed in several breeds, including the Beagle and Fox Terrier. The third major pattern is called extreme white and results in a dog that is almost entirely white but usually has at least some color on the head. Furthermore, there is a pattern called mantle, this pattern is similar to Irish spotting but with more white extending onto the thigh and up the torso, as seen in some Great Danes. Another pattern that is similar to Irish spotting is called flash or pseudo-Irish and occurs in Boxers.

A mutation found in the MITF gene is associated with the piebald spotting pattern in more than 25 different dog breeds. The Coat Colour Piebald test (H326) tests for the genetic status of this mutation. It results in two variants (alleles). The allele N does not produce a piebald pattern, therefor dogs with two copies of the N allele do not display the piebald pattern. The allele S is associated with the piebald pattern, however the amount of white spotting expressed varies from breed to breed and among individuals within a breed. In many breeds such as Collie, Great Dane, Italian Greyhound, Shetland Sheepdog, Boxer and Bull Terrier, piebald behaves as a dosage-dependent trait. In those breeds the allele S is semi-dominant. One copy of the S allele (S/N) results in a limited white spotting pattern. Dogs with two copies of the S allele (S/S) display more extreme white with colour only on the head and perhaps a body spot. In Boxers and Bull Terriers, dogs that have two copies of the S allele (S/S) are completely white while dogs that only have one copy of the S allele (N/S) display the mantle pattern (called flash in these breeds). However, additional mutations in MITF or other white-spotting genes that affect the amount of white being expressed appear to be present in these breeds. In some other breeds, the allele S is recessive and in those breeds two copies are needed to produce the piebald pattern.
More information...
i H353 Coat Colour Saddle tan vs black-and-tan Basset, Pembroke Welsh Corgi € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The hnRNP associated with lethal yellow gene (RALY gene) defines whether tan points or saddle tan is expressed in Basset Hounds and Pembroke Welsh Corgi dogs. Black and tan colour is characterized by light colour on the muzzle, above the eyes (tan points) and on the undersides of the dog on otherwise dark coat. Saddle tan resembles black and tan colour but the lighter areas are expanded leaving usually only the back to have dark patch. Saddled tan dogs are usually born black-and-tan and the black recedes as the dog grows. The coat colour is further complicated by the interaction with the E-locus, K-locus, A-locus and a yet unidentified gene. In order for the saddle tan pattern or tan points to be expressed, the dog needs to have at least one copy of the E or Em allele at the E-locus, two copies of the ky allele at the K-locus and one or two copies of the at allele at the A-locus. The Coat Colour Saddle tan vs black-and-tan test (H353) tests for the genetic status of the RALY gene. The RALY gene has two variants (alleles). The allele WT is dominant and causes the saddle tan coat colour. Only when the dog has two copies of the recessive allele dup the coat colour is black-and-tan. The saddle tan coat colour is present in a limited number of dog breeds including some of the terriers, scent hounds and herding dogs. In breeds that have only tan point dogs and no saddled tan dogs, the tan pointed dogs can have any genotype for the RALY gene. This suggests that more complex interactions are behind tan points in breeds that are not able to express saddle tan.
More information...
i H921 Curly Coat All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Keratin 71 (KRT71) gene influences the hair formation. The Curly Coat test (H921) tests for the genetic status of the KRT71 gene. The KRT71 gene has two variants (alleles). The allele CC is dominant and results in a curly coat. Only when the dog has two copies of the recessive allele N the coat is of a non-curly type. Some breeds, such as the Irish Water Dog, are fixed for the dominant allele CC. Other breeds, such as Kuvasz, can have either curly or non-curly hair.
More information...
i H681 Curly Coat 2 Curly-Coated Retriever, Bichon Frise, Spanish Water Dog, Irish Terrier, Lagotto Romagnolo (Romagna Water Dog), Chesapeake Bay Retriever, Poodle, Mudi € 50,18
Curly coat is a common trait in many dog breeds. In 2009 a mutation in exon 2 of the Keratin 71 gene (KRT71) was detected which causes the curly coat phenotype. Screening of this variant in various dog breeds revealed however, that it does not explain the curly coat in all breeds. Continued research lead to the detection of a second curly coat variant in exon 7 of the KRT71 gene. This mutation is fixed in Curly Coat Retrievers and segregates in some other breeds. Additionally, there is some indication that the variant possibly represents a genetic risk factor for some forms of follicular dysplasia in dogs. More information...
i H765 Hair length All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The Fibroblast Growth Factor 5 (FGF5) determines the hair length. The Hair Length test (H765) tests for the genetic status of the FGF5-gene and has two variants (alleles). The allele S is dominant and results in short hair. Only when the dog has two copies of the recessive allele L the dog has long hair. Some breeds, such as Labradors, are fixed for the dominant allele S. Other breeds, such as Poodles, are fixed for the recessive allele L and some breeds, such as Dachshund, can have either long or short hair. In some breeds another, yet unidentified, mutation is present that influences hair length. This unidentified mutation is known to occur in Afghan Hounds, Yorkshire Terriers, and Silky Terriers.
More information...
i H848 Improper Coat/Furnishings All breeds € 50,18
During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests.

The R-spondin 2 (RSPO2) gene influences both the wiry texture and a growth pattern of the coat. The growth pattern of the coat, also known as “furnishings”, increases hair growth on the face and legs and is typified by the canine moustache and eyebrows. The term "furnishings" refers to the longer mustache and eyebrows seen in wire-haired dogs and other breeds. In breeds such as the Portuguese Water Dog, Labradoodle and Goldendoodles furnishings can be variable, but are the breed standard. Portuguese Water Dogs without furnishings are referred to as having an "Improper Coat" which is characterized by short hair on the head, face and legs. The Improper Coat/Furnishings test (H848) tests for the genetic status of the RSPO2 gene. The RSPO2 gene has two variants (alleles). The allele N is dominant and results in “furnishings”. Only when the dog has two copies of the recessive allele IC the dog does not have “furnishings”. Some breeds, such as the Airedale Terrier, are fixed for the dominant allele N.
More information...